Abstract
RYGB was considered as an effective treatment for obese patients with T2D. However, 5-year outcomes including T2D remission after surgery have not been adequately studied in Chinese patients. Our aim is to evaluate metabolic outcomes of RYGB in 5-year follow-up. We retrospectively divided 59 Chinese patients into two groups, namely BMI groups (group A: BMI < 28 kg/m2; group B: BMI ≥ 28 kg/m2) and A1C groups (group C: A1C < 7%; group D: A1C ≥ 7%). Their medical records were collected and cardiovascular risk and medications were evaluated in 5 years after RYGB. Thirty patients were female (30/59, 50.85%). RYGB was performed laparoscopically without mortality or major complications. The mean BMI in 59 patients decreased from 30.89 ± 3.12 to 25.04 ± 3.48 in the fifth year. No one was lost to follow-up in 5 years. There were significant reductions in BMI, A1C, and oral medication or insulin in all groups. Diabetes remission rates in the first, third, and fifth years postoperation were 77.97, 61.02, and 49.15%. T2D relapse and requirement for antihypertensive agents increased in the third and fifth years. Larger quantity of subcutaneous fat area (SFA) and shorter duration of T2D preoperation were more likely to achieve remission of T...Continue Reading
References
Jan 11, 2001·Diabetologia·C WeyerR E Pratley
Jan 30, 2002·Diabetes Care·John B Dixon, Paul E O'Brien
Feb 12, 2009·Journal of Occupational and Environmental Medicine·Nathan L KleinmanHarold H Gardner
Sep 11, 2009·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Malin LönnLauren Lissner
Nov 26, 2009·Annals of Surgery·Francesco RubinoUNKNOWN Diabetes Surgery Summit Delegates
May 21, 2010·Annals of Surgery·Seongmin Kim, William O Richards
Sep 11, 2010·Diabetologia·J HoffstedtP Arner
Jul 26, 2011·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·J B DixonUNKNOWN International Diabetes Federation Taskforce on Epidemiology and Prevention
Oct 4, 2012·Diabetes Care·John B DixonWei-Jei Lee
Jan 29, 2013·Obesity Surgery·M RobertC Thivolet
Apr 19, 2013·Obesity Facts·Hongtao YanFuzhou Tian
Mar 19, 2014·Diabetes Research and Clinical Practice·L GuariguataJ E Shaw
Apr 25, 2014·Diabetes Care·Daniel P AnderssonPeter Arner
Dec 31, 2014·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Haoyong YuWeiping Jia
Sep 28, 2015·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Nabeel R ObeidChristine J Ren-Fielding
Jun 18, 2016·Obesity Surgery·Hongwei ZhangWeiping Jia
Feb 6, 2017·International Journal of Obesity : Journal of the International Association for the Study of Obesity·C MerlottiA E Pontiroli
Mar 21, 2018·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Owaid M AlmalkiShu-Chun Chen
May 31, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Lei ZhaoShaihong Zhu
Nov 6, 2018·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Xin HuangShaozhuang Liu
Aug 3, 2019·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Mona A HegazyMervat E Behiry
Citations
Dec 29, 2020·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Zhigang KeWeidong Tong
Oct 17, 2020·Obesity Surgery·Zhigang KeWeidong Tong
Jul 11, 2021·Obesity Surgery·Yichen LiZhongqi Mao
Aug 4, 2021·Obesity Surgery·Wah YangUNKNOWN Chinese Obesity and Metabolic Surgery Collaborative
Jul 10, 2021·Journal of Molecular Cell Biology·Yinfang TuPin Zhang
Sep 11, 2021·Obesity Surgery·Zhiqing YuYoucheng Zhang