Royal Jelly Supplementation Improves Menopausal Symptoms Such as Backache, Low Back Pain, and Anxiety in Postmenopausal Japanese Women

Evidence-based Complementary and Alternative Medicine : ECAM
Takashi AsamaTakashi Takeda

Abstract

This study aimed to evaluate the effect of Royal Jelly (RJ) at a dose of 800 mg/day on menopausal symptoms in healthy Japanese postmenopausal women with placebo-controlled design. A total of 42 healthy Japanese postmenopausal women have been recruited for this study. The subjects were randomized to oral treatment with either 800 mg of protease-digested lyophilized powder of RJ (enzyme-treated RJ) or placebo (800 mg of dextrin) daily for 12 weeks. The level of menopausal symptoms has been evaluated every 4 weeks, using menopausal symptoms questionnaire of Japanese women. Independent t-test was used to evaluate statistical significance of the treatment effects between the two groups. All of the 42 women have completed the trial. There were significant differences related to the anxiety score (P = 0.046) and backache and low back pain score (P = 0.040) between 800 mg/day enzyme-treated RJ and placebo-treated groups after 12 weeks of administration, and no significant differences were found between the two groups in 4 weeks after intervention. No side effects were observed in either group. This study demonstrates that enzyme-treated RJ supplementation with doses of 800 mg/day is effective in relieving menopausal symptoms such as an...Continue Reading

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Citations

Sep 25, 2019·International Journal of Molecular Sciences·Hiroshi Kunugi, Amira Mohammed Ali
Jul 17, 2020·Archives of Gynecology and Obstetrics·Karsten Münstedt, Heidrun Männle
Jul 24, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Andreea BălanCostin Vlad Anastasiu
Sep 4, 2020·Climacteric : the Journal of the International Menopause Society·H MatsushitaA Wakatsuki

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Methods Mentioned

BETA
light scattering

Software Mentioned

SAS
JMP

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