Running Dose and Risk of Developing Lower-Extremity Osteoarthritis

Current Sports Medicine Reports
Trevor Gessel, Mark A Harrast

Abstract

Whether or not running leads to the development of knee and hip osteoarthritis has been a much-debated topic and is often a question patients pose to their physicians. Recent literature adds to a growing body of evidence suggesting that lower-dose running may be protective against the development of osteoarthritis, whereas higher-dose running may increase one's risk of developing lower-extremity osteoarthritis. However, running dose remains challenging to define, leading to difficulty in providing firm recommendations to patients regarding the degree of running which may be safe. Furthermore, when counseling patients regarding their risk of developing lower-extremity osteoarthritis secondary to running, clinicians must consider many additional factors, such as the numerous health benefits from running and individual risk factors for developing osteoarthritis.

References

May 24, 1975·British Medical Journal·J PuranenJ Saarela
Jun 1, 1983·British Journal of Sports Medicine·M McDermott, P Freyne
Jan 22, 1994·BMJ : British Medical Journal·U M KujalaS Sarna
Sep 1, 1995·Bone·L Mosekilde
Jan 13, 2000·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·C T ChenJ M Tekoppele
Feb 14, 2002·Osteoarthritis and Cartilage·E LucchinettiP A Torzilli
Jan 28, 2003·British Journal of Sports Medicine·M BurrowsD Simpson
Feb 16, 2005·Current Opinion in Rheumatology·Ewa M Roos
Jun 28, 2005·Osteoarthritis and Cartilage·Velandai K SrikanthGraeme Jones
May 1, 2007·Medicine and Science in Sports and Exercise·Paul T Williams
Sep 6, 2007·Journal of Cellular Physiology·Mary B Goldring, Steven R Goldring
Jan 16, 2008·Clinical Orthopaedics and Related Research·Reinhold GanzWilliam H Harris
Jan 19, 2008·Medicine and Science in Sports and Exercise·Paul T Williams
Feb 7, 2009·Journal of Strength and Conditioning Research·R Scott RectorPamela S Hinton
Oct 7, 2009·Arthritis Research & Therapy·Jorge A Roman-BlasGabriel Herrero-Beaumont
Mar 10, 2010·Scandinavian Journal of Medicine & Science in Sports·E W HelgeP Krustrup
Jun 1, 2010·Annals of the Rheumatic Diseases·Leena SharmaMichael Nevitt
Aug 12, 2010·Clinics in Geriatric Medicine·Yuqing Zhang, Joanne M Jordan
Jul 28, 2011·Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders·Hui B SunHiroki Yokota
Sep 29, 2011·PM & R : the Journal of Injury, Function, and Rehabilitation·Adam S Tenforde, Michael Fredericson
Nov 5, 2011·Medicine and Science in Sports and Exercise·John J DubéFrancesca Amati
Jul 26, 2012·Sports Medicine·Alexandre Dias LopesLeonardo Oliveira Pena Costa
Aug 1, 2012·Nature Reviews. Rheumatology·Kim BennellBill Vicenzino
Aug 15, 2012·Scandinavian Journal of Medicine & Science in Sports·N HamannA Niehoff
Jan 15, 2013·Rheumatic Diseases Clinics of North America·Tuhina Neogi, Yuqing Zhang
Feb 5, 2013·Medicine and Science in Sports and Exercise·Paul T Williams
Jun 26, 2013·PM & R : the Journal of Injury, Function, and Rehabilitation·Heather K Vincent, Kevin R Vincent
Mar 26, 2014·Nature Reviews. Rheumatology·David J HunterEmily Callander
May 6, 2014·Best Practice & Research. Clinical Rheumatology·Victoria L Johnson, David J Hunter
Jan 22, 2015·Arthritis & Rheumatology·Matthew J KosterVaidehi R Chowdhary
Dec 2, 2015·BMC Public Health·Ronald PlotnikoffKim Raine
Feb 26, 2016·Annals of Physical and Rehabilitation Medicine·Clémence PalazzoSerge Poiraudeau

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Citations

Jun 3, 2021·Journal of Orthopaedic Surgery and Research·Ni ZengGuo-Xin Ni
Sep 21, 2021·Sports Medicine·Volker ScheerDaniel Rojas-Valverde

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