Rupture of major vessels after radiation.

Cancer
L F Fajardo, A Lee

Abstract

Rupture of irradiated large vessels is an uncommon complication which tends to occur in carotid, aorta, and femoral arteries, in decreasing order of incidence. It particularly affects men subjected to surgery and radiotherapy for epidermoid carcinomas in oropharynx, esophagus, or genitalia. Contrary to some opinion, radiation is not the most significant cause; this "spontaneous" arterial rupture can occur without radiation. The perforation is not associated with tumor invasion of arterial wall, as has been claimed. Surgical complications, especially necrosis of skin flaps, infection, and fistulas are most important etiologically. Only 2 of the 11 instances that we describe appear to have been caused mainly by radiation. The perforation is usually fatal, but several patients, including 3 of our series (2 carotid, 1 femoral), have been saved by hospital personnel aware of this complication. To prevent it, prolonged exposure or infection of arteries, whether irradiated or not, should be avoided.

References

Feb 1, 1972·The Journal of Urology·D G SkinnerS B Kelley
Mar 1, 1972·Archives of Otolaryngology·C S McConnel, F I Marlowe
May 1, 1972·The British Journal of Surgery·H B Ross, J E Sales
Nov 1, 1971·Radiology·L F Fajardo, J R Stewart
Dec 1, 1969·The British Journal of Radiology·A G JohnsonN W Ramsay
Jul 1, 1968·Journal of Clinical Pathology·G JeanT Ranzi
Apr 1, 1969·The Surgical Clinics of North America·E W Strong
Jan 1, 1969·Archives of Surgery·J C HegartyE D McSweeney
Oct 1, 1965·American Journal of Surgery·A S Ketcham, R C Hoye
May 1, 1966·Archives of Otolaryngology·A A RoscherJ S Woodard
Aug 1, 1967·Archives of Otolaryngology·H B Cheek, E N Rise
Dec 1, 1967·Annals of Internal Medicine·J F FraumeniJ M Kissane
Apr 1, 1959·A.M.A. Archives of Otolaryngology·J W McCALLE L HENDERSHOT
Sep 1, 1960·Acta Radiologica·O BARTLEY, C G HELANDER
Dec 1, 1962·The Annals of Otology, Rhinology, and Laryngology·R A MARCIAL-ROJAS, J R CASTRO
Jul 1, 1964·Journal of Atherosclerosis Research·G D AMROMINB B NADKARNI
Jun 1, 1965·American Journal of Surgery·D G DIBBELLD P SHEDD
Jan 1, 1962·Circulation Research·S LINDSAYJ JEW

❮ Previous
Next ❯

Citations

Jan 1, 1986·Cardiovascular and Interventional Radiology·J Husted, D Dempsey
Jan 1, 1994·Seminars in Roentgenology·V P Chuang
Oct 1, 1993·Seminars in Roentgenology·E M Loyer, E S Delpassand
Mar 7, 2001·Cardiovascular Radiation Medicine·M P TallmanR M Pomerantz
Nov 7, 2001·Cardiology in Review·M Y Salame, J S Douglas
Aug 17, 2012·Current Opinion in Otolaryngology & Head and Neck Surgery·John R de Almeida, Eric M Genden
Apr 1, 1990·Clinical Otolaryngology and Allied Sciences·R L Carter
Sep 1, 2008·Case Reports in Gastroenterology·Francesco PuccioMassimiliano Solazzo
Feb 22, 2000·Radiographics : a Review Publication of the Radiological Society of North America, Inc·B MesurolleD Vanel
Apr 1, 1986·The British Journal of Radiology·R Uflacker
May 1, 1990·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·C E LindholmO Ljungberg
Jun 22, 2010·Annales de chirurgie plastique et esthétique·F M P LeclèreM Schoofs
Dec 26, 2015·Journal of Bronchology & Interventional Pulmonology·Erik FolchAdnan Majid
Dec 1, 1988·International Journal of Radiation Oncology, Biology, Physics·E L GilletteS J Withrow
May 1, 1987·International Journal of Radiation Oncology, Biology, Physics·P J HoopesS J Withrow
Jul 1, 1995·Journal of Vascular and Interventional Radiology : JVIR·M L LukensP S Fox
Mar 5, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Jaden D EvansJames W Welsh
Feb 1, 1986·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·E M RosenS E Levenson
Feb 14, 2007·International Journal of Cardiology·Nicola CiabattiAnna Sonia Petronio
Dec 4, 2003·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·B H A von RahdenJ R Siewert
Jan 5, 2005·International Journal of Radiation Oncology, Biology, Physics·Patrick W McLaughlinMarc Kessler
Oct 1, 1978·Gynecologic Oncology·T H KwonJ D Hardy
Mar 1, 1991·Progress in Cardiovascular Diseases·M A Arsenian
Mar 1, 1991·Current Problems in Surgery·H A Gelabert, W S Moore
Feb 1, 1984·The British Journal of Surgery·V Moshakis, R L Carter
Jan 1, 1986·Seminars in Surgical Oncology·P D Himmel, J M Hassett
May 1, 1985·Histopathology·P S HasletonP F Schofield
Feb 1, 1990·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·P PiedboisJ P Le Bourgeois
Jan 10, 2012·International Journal of Radiation Biology·Gabriel S KrigsfeldAnn R Kennedy
Jul 13, 2012·Journal of Plastic Surgery and Hand Surgery·Masayuki OkochiHirotaka Asato
Dec 12, 2001·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·R PararajasingamT O Oshodi
Jan 1, 1978·Cancer·G D SilverbergD R Goffinet
Jul 1, 1980·Cancer·R R Miller, D H McGregor
Apr 26, 2005·Acta Oncologica·Luis Felipe Fajardo
Apr 13, 2005·Pediatric Blood & Cancer·Gerald J Berry, Michelle Jorden
Jan 13, 1998·The Journal of Laryngology and Otology·N ZidarE Soba
Nov 5, 2019·Hypertension·Matthias Barton, Masashi Yanagisawa
Jul 1, 1985·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·E M RosenS E Levenson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.