Rush immunotherapy: experience with a one-day schedule

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
P Sharkey, J Portnoy

Abstract

Rush immunotherapy is a method for rapidly desensitizing patients to inhalant allergens. The frequency of systemic reactions during rush immunotherapy is similar to conventional immunotherapy when premedication is used. The most rapid protocol for rush immunotherapy reported to date requires one and one-half days which is inconvenient to patients and clinic schedules. To improve this situation and decrease the cost of giving rush immunotherapy, we have developed a 1-day protocol. for this ongoing study, 22 allergic patients received rush immunotherapy consisting of eight injections over six hours followed by two hours of observation in an outpatient clinic. Five had rhinitis and the rest has asthma, seven of whom were steroid-dependent. All were premedicated with astemizole, ranitidine, and prednisone for three days including the day of rush immunotherapy, and peak expiratory low rates were monitored. Systemic reactions were seen in five of 22 (23%). They occurred following the sixth injection (1), seventh injection (2), or the final one (2) and consisted primarily of rhinitis or pulmonary symptoms with one episode of mild anaphylaxis. A systemic reaction was seen in only one steroid-dependent asthmatic patient. A local reactio...Continue Reading

References

Apr 1, 1978·The Journal of Allergy and Clinical Immunology·W J MetzgerR Patterson
Oct 1, 1992·The Journal of Allergy and Clinical Immunology·G E Stewart, R F Lockey
May 1, 1992·The Journal of Allergy and Clinical Immunology·A HejjaouiJ Bousquet
Dec 1, 1989·The Journal of Allergy and Clinical Immunology·D I BernsteinI L Bernstein
Jul 1, 1994·The Journal of Allergy and Clinical Immunology·J Bousquet, F B Michel
Mar 1, 1993·The Journal of Allergy and Clinical Immunology·J R Cohn, A Pizzi

❮ Previous
Next ❯

Citations

Jun 1, 2000·Clinical Reviews in Allergy & Immunology·P A Greenberger
Jun 4, 2013·Current Allergy and Asthma Reports·Christopher W Calabria
May 10, 2005·Immunology and Allergy Clinics of North America·Mark H Moss
Aug 30, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Linda Cox
Feb 25, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Ira Finegold
Apr 24, 2004·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Shelly M HarveyDavid A Khan
Oct 3, 1999·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·R Patterson, K E Harris
Jan 1, 1997·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·G Gurka
Dec 24, 2005·International Archives of Allergy and Immunology·M CasanovasE Fernández-Caldas
Dec 9, 2014·Expert Review of Clinical Immunology·Marco CaminatiGiorgio Walter Canonica
May 3, 2011·Immunology and Allergy Clinics of North America·Christopher W Calabria, Linda Cox
Jul 16, 2008·The Journal of Allergy and Clinical Immunology·Linda Cox
Oct 6, 2007·The Journal of Allergy and Clinical Immunology·UNKNOWN Joint Task Force on Practice ParametersUNKNOWN Joint Council of Allergy, Asthma and Immunology
Mar 6, 2007·The Journal of Allergy and Clinical Immunology·Harold S Nelson
Mar 27, 2009·Veterinary Dermatology·Christine Loewenstein, Ralf S Mueller
Sep 12, 2009·Current Opinion in Allergy and Clinical Immunology·Harold S Nelson
Jul 4, 2008·Current Opinion in Allergy and Clinical Immunology·Michael S Tankersley
Oct 25, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Christopher C CopenhaverSteven Patch
Jul 1, 2006·Expert Review of Clinical Immunology·Linda Cox
Dec 3, 2010·The Journal of Allergy and Clinical Immunology·Linda CoxDana Wallace
Jun 30, 2021·The Journal of Allergy and Clinical Immunology·Suzanne C MorrisFred D Finkelman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

Related Papers

The Journal of Allergy and Clinical Immunology
David I BernsteinImmunotherapy Committee, American Academy of Allergy, Asthma and Immunology
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Shelly M HarveyDavid A Khan
© 2021 Meta ULC. All rights reserved