Ruthenium-catalyzed synthesis of allylic alcohols: boronic acid as a hydroxide source

Chemistry : a European Journal
Asmae BouzianeJean-Luc Renaud

Abstract

Secondary allylic alcohols were synthesized from linear allylic halides or carbonates using a catalytic amount of a ruthenium complex in the presence of boronic acid. The effects of solvent, base, ruthenium precursor, and boronic acid were fully explored, and the scope of the reaction was extended to various substrates. We also describe a preliminary investigation towards an enantioselective process.

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Citations

Jun 10, 2015·Chemical Communications : Chem Comm·Naoya KanbayashiKiyotaka Onitsuka
Jul 21, 2015·Angewandte Chemie·Xinjiang CuiMatthias Beller
Dec 21, 2017·Beilstein Journal of Organic Chemistry·Markéta BláhováJindřich Jindřich
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Jun 19, 2013·The Journal of Organic Chemistry·Rémy HemelaereBertrand Carboni
Jan 12, 2019·The Journal of Organic Chemistry·Milan K BarmanBiplab Maji
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Aug 29, 2019·ACS Omega·João Victor Santiago, Antonio C B Burtoloso
Oct 22, 2021·The Journal of Organic Chemistry·Travis MenardScott E Denmark

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