S100A7 and the progression of breast cancer

Breast Cancer Research : BCR
Ethan D EmberleyPeter H Watson

Abstract

The S100 gene family comprises more than 20 members whose protein sequences encompass at least one EF-hand Ca2+ binding motif. The expression of individual family members is not ubiquitous for all tissues and there appears to be an element of tissue-specific expression. Molecular analysis of breast tumors has revealed that several S100s, including S100A2, S100A4 and S100A7, exhibit altered expression levels during breast tumorigenesis and/or progression. Subsequent studies have started to describe a functional role for these S100 proteins as well as their mechanism of action and the biochemical pathways they modify. The present review outlines what is known about S100A7 in breast cancer and summarizes the need to better understand the importance of this protein in breast cancer.

References

Mar 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·S W LeeR Sager
Feb 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·P Masiakowski, E M Shooter
Oct 9, 1995·International Journal of Cancer. Journal International Du Cancer·C Moog-LutzP Basset
Jan 1, 1994·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R Barraclough, P S Rudland
Jun 1, 1996·The Journal of Urology·J E CelisT F Orntoft
Jul 1, 1996·The Journal of Investigative Dermatology·T JinquanK Thestrup-Pedersen
Sep 17, 1996·International Journal of Cancer. Journal International Du Cancer·M GrigorianE Lukanidin
Nov 4, 1996·International Journal of Cancer. Journal International Du Cancer·E C IlgC W Heizmann
Aug 7, 1998·The International Journal of Biochemistry & Cell Biology·P H WatsonL C Murphy
Jan 27, 1999·Biochimica Et Biophysica Acta·R Barraclough
Dec 14, 1999·The American Journal of Pathology·S Al-HaddadP H Watson
Aug 30, 2000·Nature·C M PerouD Botstein
Oct 4, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·V GakiD A Spandidos
Nov 15, 2000·British Journal of Cancer·D LiuR Barraclough
Mar 22, 2001·Biochemistry·M RuseR L Eckert
Apr 17, 2001·Laboratory Investigation; a Journal of Technical Methods and Pathology·N NagyC Decaestecker
Nov 15, 2001·The Journal of Biological Chemistry·Moon-Kyoung BaeKyu-Won Kim
Feb 26, 2003·BMC Dermatology·Salem AlowamiPeter H Watson
Mar 20, 2003·Microscopy Research and Technique·Rosario Donato
Apr 22, 2003·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Ann-Marie BroomeRichard L Eckert
Aug 19, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Ronald WolfThomas Ruzicka
Jan 8, 2004·British Journal of Cancer·S R JenkinsonP S Rudland

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Citations

Dec 23, 2011·Breast Cancer Research and Treatment·Emman ShubbarCharlotta Enerbäck
Apr 2, 2005·Nature Reviews. Immunology·Michael T Lotze, Kevin J Tracey
Dec 14, 2011·Cancer Research·Mohd W NasserRamesh K Ganju
Jun 7, 2008·Breast Cancer Research : BCR·Jiaxu WangPeter H Watson
Aug 7, 2010·PloS One·Satyendra Chandra TripathiK W Michael Siu
Nov 21, 2012·Hepatitis Monthly·Claudia MaletzkiClaus Kerkhoff
Dec 23, 2004·Journal of Immunotherapy·Herbert J Zeh, Michael T Lotze
Jun 30, 2006·Expert Opinion on Biological Therapy·Christian A PetrulioHoward L Kaufman
Aug 27, 2009·Acta Oto-laryngologica·Ki Hyung KimSungwon Chae
Jul 19, 2006·Biochemical Pharmacology·Christoffer GebhardtJochen Hess
Jan 25, 2007·Journal of the European Academy of Dermatology and Venereology : JEADV·S GregoriouE Koumantaki
Oct 22, 2009·Protein Science : a Publication of the Protein Society·Nathan R WestMartin J Boulanger
Jan 24, 2015·Nature Reviews. Cancer·Anne R BresnickDanna B Zimmer
May 30, 2012·Proteomics. Clinical Applications·Patrizia CancemiIda Pucci-Minafra
May 26, 2017·Virchows Archiv : an International Journal of Pathology·Norbert NassThomas Kalinski
Dec 19, 2019·Frontiers in Genetics·Jie LiYadong Wang
Jul 30, 2020·Cancers·Chantal AllgöwerJohannes Lemke
Oct 25, 2007·Biochemical Society Transactions·M M MurrayD P Harkin
Apr 25, 2019·Nature Communications·Joanna Y LeeOvijit Chaudhuri
May 24, 2020·International Journal of Molecular Sciences·Ali H El-FarShaker A Mousa
Dec 17, 2005·Cancer Research·Ian KropKornelia Polyak
Feb 5, 2008·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Audrey GagnonSamuel C Mok
Sep 20, 2017·Molecular Cancer Research : MCR·Yunguang LiXueyuan Xiao
Feb 21, 2018·Cancer Research·Venkata ManemBenjamin Haibe-Kains

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Methods Mentioned

BETA
two-hybrid

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