Abstract
To determine the adaptive capability of saccadic eye movements, and its association with enduring saccadic dysmetria in cerebellar and lateral medullary infarction (LMI), we investigated saccadic accuracy and adaptation in 15 patients with cerebellar or lateral medullary infarction, compared with those of 7 patients with diffuse cerebellar atrophy and 11 normal subjects. Saccade adaptation was elicited by a 37.5% backward target step during the primary saccade in both horizontal directions. Horizontal preadaptive saccadic gains were decreased in patients with cerebellar infarction, and contralesionally in patients with LMI. In contrast, adaptive saccadic gain change was reduced in patients with diffuse cerebellar atrophy and cerebellar infarction. Saccadic hypometria and reduced saccadic adaptability were dissociated in the majority of the patients with cerebellar infarctions; seven of the eight patients with cerebellar infarction showed saccadic hypometria and only three of them showed reduced saccadic adaptation, uni- or bilaterally in two with bilateral infarctions and ipsilesionally in one with unilateral infarction. The most commonly affected structure on MRI was the cerebellar hemisphere in the patients either with saccad...Continue Reading
References
Sep 1, 1976·Brain : a Journal of Neurology·J B SelhorstW F Hoyt
Aug 1, 1992·Brain : a Journal of Neurology·W Waespe, R Baumgartner
Dec 1, 1980·Journal of Neurophysiology·L M Optican, D A Robinson
Nov 1, 1993·Journal of Neurophysiology·F R RobinsonA F Fuchs
Nov 1, 1996·Neurology·L TatuH Duvernoy
Oct 17, 1998·Journal of Neurophysiology·M TakagiR J Tamargo
Apr 10, 1999·Nature Neuroscience·M DesmurgetS T Grafton
Jun 15, 2000·Experimental Brain Research·M DesmurgetS T Grafton
Sep 13, 2001·The European Journal of Neuroscience·B GaymardC J Ploner
Dec 12, 2001·Neurology·A StraubeT Eggert
Apr 19, 2002·Annals of the New York Academy of Sciences·F R RobinsonC T Noto
Apr 19, 2002·Annals of the New York Academy of Sciences·Laura E Mezey, Christopher M Harris
Jun 22, 2002·Brain : a Journal of Neurology·Michael R MacAskillRichard D Jones
Feb 5, 2003·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Yuuki HayakawaHaruki Abe
Jun 14, 2003·Neuroscience Research·Naoko InabaKaoru Yoshida
Aug 9, 2003·Journal of Neurophysiology·Charles A Scudder, David M McGee
Oct 1, 1963·IEEE Transactions on Bio-medical Engineering·D A ROBINSON
Oct 24, 2003·Journal of Neurophysiology·Marc A Sommer, Robert H Wurtz
Mar 17, 2004·Progress in Neurobiology·J Johanna Hopp, Albert F Fuchs
May 26, 2006·Investigative Ophthalmology & Visual Science·Elizabeth L IrvingNatalie Hutchings
Nov 24, 2006·Brain : a Journal of Neurology·Stefano RamatLance M Optican
Apr 4, 2007·Neurology·J S KimJ A Sharpe
Apr 25, 2007·Neurology·K-D ChoiJ S Kim
Citations
Aug 22, 2013·Experimental Brain Research·M PanouillèresD Pélisson
Jul 29, 2010·The Cerebellum·Ned Jenkinson, R Chris Miall
Oct 12, 2012·The Cerebellum·Esmee I M L LiemJos N van der Geest
Dec 23, 2009·Neuroscience and Biobehavioral Reviews·D PélissonC Tilikete
Jun 22, 2011·Human Brain Mapping·Muriel PanouillèresDenis Pélisson
Sep 22, 2010·Vision Research·Jing Tian, David S Zee
Nov 22, 2014·Frontiers in Neural Circuits·Ruben-Dario Pinzon-Morales, Yutaka Hirata
May 12, 2016·The Cerebellum·Aasef G ShaikhDavid S Zee
Jun 1, 2016·Frontiers in Human Neuroscience·Eckart Zimmermann, Markus Lappe
Aug 17, 2016·Neuroscience and Biobehavioral Reviews·Beth P JohnsonJoanne Fielding
Mar 14, 2014·Journal of Neurophysiology·Michael J GrayMark R Harwood
May 26, 2020·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Nico BastUNKNOWN EU-AIMS LEAP Group
Sep 20, 2016·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Shin C BehElliot M Frohman
Nov 16, 2017·Journal of Clinical Neurology·In Sung ParkIm Joo Rhyu
Jan 4, 2022·Cerebral Cortex·Alexis ChevietDenis Pélisson