Sacral nerve stimulation versus percutaneous tibial nerve stimulation for faecal incontinence: a systematic review and meta-analysis

International Journal of Colorectal Disease
Constantinos SimillisParis P Tekkis

Abstract

Percutaneous tibial nerve stimulation (PTNS) and sacral nerve stimulation (SNS) are both second-line treatments for faecal incontinence (FI). To compare the clinical outcomes and effectiveness of SNS versus PTNS for treating FI in adults. A literature search of MEDLINE, Embase, Science Citation Index Expanded and Cochrane was performed in order to identify studies comparing SNS and PTNS for treating FI. A risk of bias assessment was performed using The Cochrane Collaboration's risk of bias tool. A random effects model was used for the meta-analysis. Four studies (one randomised controlled trial and three nonrandomised prospective studies) reported on 302 patients: 109 underwent SNS and 193 underwent PTNS. All included studies noted an improvement in symptoms after treatment, without any significant difference in efficacy between SNS and PTNS. Meta-analysis demonstrated that the Wexner score improved significantly with SNS compared to PTNS (weighted mean difference 2.27; 95% confidence interval 3.42, 1.12; P < 0.01). Moreover, SNS was also associated with a significant reduction in FI episodes per week and a greater improvement in the Fecal Incontinence Quality of Life coping and depression domains, compared to PTNS on short-ter...Continue Reading

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Citations

Oct 12, 2018·Therapeutic Advances in Gastroenterology·Natalia Hounsome, Chris Roukas
Aug 26, 2020·Current Gastroenterology Reports·Brototo DebAdil E Bharucha
Feb 6, 2020·Neuromodulation : Journal of the International Neuromodulation Society·Bridget R Southwell
Aug 8, 2019·Current Urology Reports·Courtenay K MooreSamir Derisavifard
Apr 26, 2019·International Journal of Surgery·Constantinos SimillisParis P Tekkis

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