SAEFVIC: Surveillance of adverse events following immunisation (AEFI) in Victoria, Australia, 2018

Communicable Diseases Intelligence
Hazel J ClothierJim P Buttery

Abstract

SAEFVIC is the Victorian surveillance system for adverse events following immunisation (AEFI). It enhances passive surveillance by also providing clinical support and education to vaccinees and immunisation providers. This report summarises surveillance, clinical and vaccine pharmacovigilance activities of SAEFVIC in 2018. A retrospective observational cohort study of AEFI reports received by SAEFVIC in 2018, compared with previous years since 2008. Data were categorised by vaccinee demographics of age, sex, pregnancy and Indigenous status, vaccines administered and AEFI reactions reported. Age cohorts were defined as infant (0-12 months); young child (1-4 years); school-aged (5-17 years); adult (18-64 years); and older person (65+ years). Proportional reporting ratios were calculated for signal investigation of serious adverse neurological events with all vaccines and with influenza vaccines. Clinical support services and educational activities are described. SAEFVIC received 1730 AEFI reports (26.8 per 100,000 population), with 9.3% considered serious. Nineteen percent (n = 329) attended clinical review. Annual AEFI reporting trends increased for infants, children and older persons, but were stable for school-aged and adult c...Continue Reading

References

May 13, 2006·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Lorna Hazell, Saad A W Shakir
Jun 4, 2013·The Medical Journal of Australia·Hazel J ClothierNigel W Crawford
Feb 13, 2014·BMC Public Health·Cheryl L GibbonsUNKNOWN Burden of Communicable diseases in Europe (BCoDE) consortium
Mar 20, 2014·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Keith B HoffmanBrian M Overstreet
Dec 9, 2014·Human Vaccines & Immunotherapeutics·Hazel J ClothierJim P Buttery
Dec 14, 2016·Australian and New Zealand Journal of Public Health·Marnix MusMieke van Driel
Mar 28, 2017·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Hazel J ClothierJim P Buttery
Nov 19, 2019·Communicable Diseases Intelligence·Brynley HullFrank Beard
Mar 18, 2020·Communicable Diseases Intelligence·Aditi DeyKristine Macartney

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