[Safety and acceptability of the 52 mg levonorgestrel-releasing intrauterine system in women with abnormal uterine bleeding in an ambulatory care center in Bogotá, Colombia, 2012-2016].

Revista colombiana de obstetricia y ginecología
Patricia Sandoval-Vivas


To describe safety and acceptability with the use of the 52-mg levonorgestrel-releasing intrauterine system in women with abnormal uterine bleeding. Retrospective cohort of women 18 years of age and older diagnosed with abnormal uterine bleeding, ultrasound-reported uterine length between 6 and 10 cm and uniform endometrial cavity in its entire length, regardless of structural abnormality, who received treatment with 52-mg levonorgestrel-releasing intrauterine system between 2012 and 2016. Non-probabilistic convenience sampling was carried out. Sociodemographic and clinical baseline variables were measured, as well as patient perception of bleeding and the frequency of failure, amenorrhea, need for hysterectomy and adverse events, over a 12-month follow-up period. Descriptive statistics were applied. Overall, 200 patients were assessed. A subjective perception of improvement in terms of bleeding volume and frequency of leave of absence or visits to the emergency department was found; 90 % of the patients had amenorrhea, and 6 % experienced adverse events. The 52-mg levonorgestrel-releasing intrauterine system is a safe option for the management of abnormal uterine bleeding in women with normal uterine size and no submucosal end...Continue Reading


Jul 31, 1999·British Journal of Obstetrics and Gynaecology·C P Spencer, M I Whitehead
Mar 29, 2003·Journal of Clinical Pathology·V PhillipsW G McCluggage
May 10, 2003·Fertility and Sterility·Vera GrigorievaAnton Mikhailov
Jun 14, 2003·The Cochrane Database of Systematic Reviews·J MarjoribanksC Farquhar
Apr 2, 2005·Obstetrics and Gynecology·Svetlana RogovskayaVladimir Kulakov
Mar 17, 2007·Fertility and Sterility·Ian S FraserWriting Group for this Menstrual Agreement Process
May 29, 2007·Contraception·Catherine d'Arcangues
Nov 16, 2007·Fertility and Sterility·Andrea S LukesGowthami Arepally
Oct 31, 2008·Journal of Minimally Invasive Gynecology·Muzeyyen GunesMetin Kaplan
Jun 6, 2009·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Jan EndrikatMichel Fortier
Aug 27, 2009·Therapeutics and Clinical Risk Management·Megan N Beatty, Paul D Blumenthal
Nov 3, 2010·American Journal of Obstetrics and Gynecology·Oskari HeikinheimoJorma Paavonen
Feb 25, 2011·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Malcolm G MunroFIGO Working Group on Menstrual Disorders
Mar 23, 2011·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Lena MarionsInger Øverlie
Jun 3, 2011·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Andra H JamesRochelle Winikoff
Oct 20, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Oskari Heikinheimo, Kristina Gemzell-Danielsson
Jan 11, 2013·The New England Journal of Medicine·Eve Espey
Dec 25, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·Malcolm G MunroIan S Fraser
Jun 13, 2017·Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia·Cristina Laguna Benetti-PintoJosé Maria Soares Júnior
Sep 11, 2018·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Malcolm G MunroFIGO Menstrual Disorders Committee
Sep 20, 2019·The Cochrane Database of Systematic Reviews·Magdalena Bofill RodriguezCindy Farquhar
Jun 13, 2020·The Cochrane Database of Systematic Reviews·Magdalena Bofill RodriguezVanessa Jordan

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Nodding Syndrome

Nodding Syndrome is a neurological and epileptiform disorder characterized by psychomotor, mental, and growth retardation. Discover the latest research on Nodding Syndrome here.

LRRK2 & Microtubules

Mutations in the LRRK2 gene are risk-factors for developing Parkinson’s disease (PD). LRRK2 mutations in PD have been shown to enhance its association with microtubules. Here is the latest research.