Safety and Effectiveness of CyPass Supraciliary Micro-Stent in Primary Open-Angle Glaucoma: 5-Year Results from the COMPASS XT Study

American Journal of Ophthalmology
George ReissStephen Lane

Abstract

To characterize the long-term (up to 5 years) safety and effectiveness of the supraciliary Micro-Stent (Alcon) implanted at the time of phacoemulsification in eyes with coexisting open-angle glaucoma (OAG) and visually significant cataract. Three-year safety extension of a 2-year randomized clinical trial. Patients from the multicenter Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery (COMPASS) trial who underwent Micro-Stent implantation plus phacoemulsification (n = 215) or phacoemulsification alone (n = 67) were evaluated 36, 48, and 60 months postoperatively. The primary outcome measurement was the occurrence of sight-threatening ocular adverse events. Evaluations at each time point included best-corrected visual acuity (BCVA), anterior and posterior segment examinations, tonometry, gonioscopy, pachymetry, perimetry, specular microscopy, and assessment of adverse events. Three sight-threatening ocular adverse events occurred, 2 in the Micro-Stent group and 1 in the control group, but none of these events was related to the Micro-Stent device. Ocular adverse events were of similar frequencies in both groups, the most common of which were BCVA loss of ≥2 lines co...Continue Reading

References

Oct 24, 2006·American Journal of Ophthalmology·Steven J GeddeJoyce C Schiffman
Jul 14, 2007·Ophthalmology·M Cristina LeskeUNKNOWN EMGT Group
Dec 27, 2013·Journal of Ophthalmology·Lívia M Brandão, Matthias C Grieshaber
Feb 27, 2018·Ophthalmology·Steven J GeddeUNKNOWN Primary Tube Versus Trabeculectomy Study Group

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Citations

Sep 14, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Christoph Faschinger
Aug 10, 2020·Journal of Glaucoma·Julián García FeijoóUNKNOWN STAR-II Investigators
Sep 17, 2020·Annual Review of Vision Science·David J Mathew, Yvonne M Buys
Jul 14, 2020·Journal of Cataract and Refractive Surgery·Steven R SarkisianUNKNOWN ASCRS Glaucoma Clinical Committee
Aug 3, 2020·Journal of Glaucoma·Arvi-Matti KuusniemiMika Harju
Jan 22, 2021·European Journal of Ophthalmology·Martina MenchiniMichele Figus
Dec 15, 2020·Current Opinion in Ophthalmology·Kateki Vinod, Steven J Gedde
May 13, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Stefan SteinerClemens Vass
May 29, 2021·The Cochrane Database of Systematic Reviews·Amanjeet SandhuGus Gazzard
May 27, 2021·International Ophthalmology·Sofia FiliMarkus Kohlhaas

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