Safety and effectiveness of large volume coils in the treatment of small aneurysms

Journal of Neurointerventional Surgery
Zsolt KulcsárBlaise Baxter

Abstract

Large volume soft design coils facilitate quicker aneurysm filling and high packing density. Our purpose was to analyze the feasibility, safety, and effectiveness of the Penumbra Coil 400 (PC400) system in the treatment of small aneurysms. A retrospective analysis of prospective data collected at three different centers was performed on consecutive aneurysms <10 mm treated with the PC400 system. A total of 92 aneurysms were included in the study. Feasibility, procedure safety, angiographic and clinical results, and follow-up results were evaluated. Mean aneurysm size was 5.8±2.0 mm. An average of 2.5±1.3 coils with a mean length of 18±16 cm per aneurysm was used, resulting in a mean packing density of 45.6±14.4%. The thromboembolic event rate was 3.3% and no procedural aneurysm rupture was observed. Immediate adequate occlusion was achieved in 66% of aneurysms. During a mean follow-up period of 7.4 months the number of adequate occlusions increased to 91%. Large volume PC 400 coils are safe and effective in the treatment of small aneurysms with a low thromboembolic complication rate and no hemorrhagic events. High packing densities are achieved with a low average number of coils used per aneurysm treated. The aneurysms demonstr...Continue Reading

References

Sep 8, 2001·Stroke; a Journal of Cerebral Circulation·D RoyJ Raymond
Jun 13, 2009·Stroke; a Journal of Cerebral Circulation·Sandra P FernsCharles B L M Majoie
Aug 14, 2010·AJNR. American Journal of Neuroradiology·A M O'HareJ M Thornton
Apr 2, 2011·Stroke; a Journal of Cerebral Circulation·Sandra P FernsUNKNOWN LOTUS Study Group
Aug 25, 2011·Clinical Neurology and Neurosurgery·Shah-Naz Hayat KhanAndrew J Ringer
Mar 17, 2012·AJNR. American Journal of Neuroradiology·E CrobedduH J Cloft
Sep 21, 2012·Journal of Neurointerventional Surgery·Justin R MascitelliAman B Patel
Mar 19, 2013·Journal of Neurointerventional Surgery·James MilburnRaisa Coral Martinez
Sep 7, 2013·AJNR. American Journal of Neuroradiology·M J van AmerongenR H M A Bartels

❮ Previous
Next ❯

Citations

Jun 3, 2017·Clinical Neuroradiology·Andreas SimgenWolfgang Reith

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.