Abstract
Large volume soft design coils facilitate quicker aneurysm filling and high packing density. Our purpose was to analyze the feasibility, safety, and effectiveness of the Penumbra Coil 400 (PC400) system in the treatment of small aneurysms. A retrospective analysis of prospective data collected at three different centers was performed on consecutive aneurysms <10 mm treated with the PC400 system. A total of 92 aneurysms were included in the study. Feasibility, procedure safety, angiographic and clinical results, and follow-up results were evaluated. Mean aneurysm size was 5.8±2.0 mm. An average of 2.5±1.3 coils with a mean length of 18±16 cm per aneurysm was used, resulting in a mean packing density of 45.6±14.4%. The thromboembolic event rate was 3.3% and no procedural aneurysm rupture was observed. Immediate adequate occlusion was achieved in 66% of aneurysms. During a mean follow-up period of 7.4 months the number of adequate occlusions increased to 91%. Large volume PC 400 coils are safe and effective in the treatment of small aneurysms with a low thromboembolic complication rate and no hemorrhagic events. High packing densities are achieved with a low average number of coils used per aneurysm treated. The aneurysms demonstr...Continue Reading
References
Sep 8, 2001·Stroke; a Journal of Cerebral Circulation·D RoyJ Raymond
May 1, 2004·Radiology·Menno SluzewskiDouwe Wijnalda
May 6, 2006·Stroke; a Journal of Cerebral Circulation·Ron C GabaTim W Malisch
Feb 13, 2007·Radiology·Michel PiotinJacques Moret
Aug 19, 2007·AJNR. American Journal of Neuroradiology·A K WakhlooI Linfante
Oct 10, 2008·AJNR. American Journal of Neuroradiology·P M White, J Raymond
Jun 13, 2009·Stroke; a Journal of Cerebral Circulation·Sandra P FernsCharles B L M Majoie
Aug 14, 2010·AJNR. American Journal of Neuroradiology·A M O'HareJ M Thornton
Apr 2, 2011·Stroke; a Journal of Cerebral Circulation·Sandra P FernsUNKNOWN LOTUS Study Group
May 17, 2011·Lancet·Philip M WhiteUNKNOWN HELPS trial collaborators
Aug 25, 2011·Clinical Neurology and Neurosurgery·Shah-Naz Hayat KhanAndrew J Ringer
Feb 11, 2012·AJNR. American Journal of Neuroradiology·R KadirvelD F Kallmes
Mar 17, 2012·AJNR. American Journal of Neuroradiology·E CrobedduH J Cloft
Jul 28, 2012·Arquivos de neuro-psiquiatria·José Ricardo VanzinJacques Moret
Sep 21, 2012·Journal of Neurointerventional Surgery·Justin R MascitelliAman B Patel
Mar 19, 2013·Journal of Neurointerventional Surgery·James MilburnRaisa Coral Martinez
May 11, 2013·AJNR. American Journal of Neuroradiology·I RezekD F Kallmes
Sep 7, 2013·AJNR. American Journal of Neuroradiology·M J van AmerongenR H M A Bartels
Jan 31, 2014·Journal of Neurointerventional Surgery·Justin R MascitelliHenry Moyle
Mar 15, 2015·AJNR. American Journal of Neuroradiology·W BrinjikjiD F Kallmes