Safety and efficacy of adjunctive cenobamate (YKP3089) in patients with uncontrolled focal seizures: a multicentre, double-blind, randomised, placebo-controlled, dose-response trial
Lancet Neurology
Nov 13, 2019
Gregory L. KraussMarc Kamin
PMID: 31734103
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Abstract
More than a third of patients with epilepsy are treatment resistant, and thus new, more effective therapies to achieve seizure freedom are needed. Cenobamate (YKP3089), an investigational antiepileptic drug, has shown broad-spectrum anticonvulsant activity in preclinical studies and sei...read more
Mentioned in this Paper
Anticonvulsants
Antiepileptic Agents
Awareness
Clinical Investigators
Double-Blind Method
Emergency Treatment
Eosinophilia
Epilepsy
Randomization
Adverse Reaction to Drug
36
30
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Safety and efficacy of adjunctive cenobamate (YKP3089) in patients with uncontrolled focal seizures: a multicentre, double-blind, randomised, placebo-controlled, dose-response trial
Abstract
More than a third of patients with epilepsy are treatment resistant, and thus new, more effective therapies to achieve seizure freedom are needed. Cenobamate (YKP3089), an investigational antiepileptic drug, has shown broad-spectrum anticonvulsant activity in preclinical studies and sei...read more
Mentioned in this Paper
Anticonvulsants
Antiepileptic Agents
Awareness
Clinical Investigators
Double-Blind Method
36
30
Related Papers
Paper Details
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- Citations
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