Safety and efficacy of infertility treatment after conservative management of borderline ovarian tumors: a preliminary report

Fertility and Sterility
Sozos J FasouliotisZev Rosenwaks

Abstract

To evaluate the safety and efficacy of infertility treatment in a group of patients after conservative management of borderline ovarian tumors. Retrospective study. University IVF unit. Five patients with previous conservative treatment of borderline ovarian tumor. Seventeen IVF cycles. Recurrence, IVF outcome. At the time of diagnosis, the mean age of the patients was 32.2 +/- 6.9 years. The mean time elapsed between the initial diagnosis of a borderline tumor and the performance of IVF was 42.2 months. After IVF, the mean number of oocytes retrieved was 7.9 +/- 4.0 with a mean fertilization rate of 57.1% and a mean number of 3.1 +/- 1.4 day 3 embryos transferred. Six pregnancies were achieved in three of the five patients with a pregnancy rate per retrieval of 37.5% and per transfer of 42.9%. The mean follow-up time that elapsed since the first IVF cycle was 39.2 months (range 9-78 months). One patient had three recurrences 13, 27, and 43 months after her first IVF cycle, all of which remained histologically serous borderline tumor. All patients were without evidence of disease at the time of last follow-up. At a mean follow-up time of 39.2 months, our results suggest that IVF may be considered for patients with conservativel...Continue Reading

References

Sep 22, 1994·The New England Journal of Medicine·M A RossingS G Self
Feb 1, 1996·Gynecologic Oncology·G M Abu-JawdehS A Cannistra
Jun 1, 1997·Fertility and Sterility·B J MosgaardA N Andersen
Dec 24, 1997·Human Reproduction·F ParazziniP G Crosignani
May 8, 1998·Gynecologic Oncology·F ParazziniE Ricci
Jul 31, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A ShushanJ G Schenker
Feb 1, 2002·American Journal of Epidemiology·Roberta B NessAnna H Wu
May 10, 2003·Fertility and Sterility·Jacques DonnezJean Squifflet
May 20, 2003·Human Reproduction Update·Philippe MoriceDamienne Castaigne
Jun 14, 2003·Seminars in Reproductive Medicine·S Kashyap, O K Davis

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Citations

Jan 22, 2008·BMC Pregnancy and Childbirth·Nadereh BehtashFahimeh Ghotbizadeh
Oct 13, 2009·Gynécologie, obstétrique & fertilité·M KoskasC Yazbeck
Apr 22, 2014·Reproductive Biomedicine Online·Manuel AlvarezPedro N Barri
Aug 29, 2014·Gynécologie, obstétrique & fertilité·J BoujenahC Poncelet
May 4, 2011·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·N E Cabenda-NarainK N Gaarenstroom
Jan 14, 2016·Human Reproduction Update·Ignacio ZapardielJuan A Garcia-Velasco
Dec 7, 2010·Fertility and Sterility·Human M FatemiPaul Devroey
Jun 16, 2015·Gynecologic Oncology Reports·Batool Hossein RashidiFirouzeh Ghaffari
Mar 30, 2016·Journal de gynécologie, obstétrique et biologie de la reproduction·J BénardM Grynberg
Oct 12, 2005·Gynecologic Oncology·Raffaele TinelliAntonio Malvasi
Feb 11, 2012·Best Practice & Research. Clinical Obstetrics & Gynaecology·Claes Göran TropéBen Davidson
Jul 10, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Isabelle CadronIgnace Vergote
Dec 6, 2017·Indian Journal of Surgical Oncology·Nidhi NayyarKapil Kumar
Aug 5, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Gina M Mantia SmaldoneRobert P Edwards

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