Safety and efficacy of the Derivo Embolization Device for the treatment of unruptured intracranial aneurysms: a multicentric study

Journal of Neurointerventional Surgery
Bastian KrausChristoph Kabbasch

Abstract

The Derivo Embolization Device (DED) is a novel flow diverter stent that provides increased x-ray visibility, an improved delivery system, and potentially reduced thrombogenicity. The objective of this study was to evaluate the early safety and efficacy of the second-generation DED. We retrospectively analyzed all patients with unruptured intracranial aneurysms (UIAs) treated with the DED between November 2015 and December 2017 in three German tertiary care centers. Procedural details, complications, and morbidity within 30 days after treatment, as well as the aneurysm occlusion rates after 6 months (O'Kelly-Marotta scale, OKM), were evaluated. Implantation of the DED was attempted in 42 patients with 42 aneurysms. All procedures were technically successful. Multiple DEDs were used in three aneurysms (7.2%) and adjunctive coiling in 11 (26.2%). Procedure-related complications occurred in four cases (9.5%) including three thromboembolic events and one aneurysm perforation. The morbidity rate was 2.4% and there was no mortality. One patient suffered an ischemic stroke with persistent aphasia at 30-day follow-up due to a thromboembolic infarct (modified Rankin Scale score 1). Among 33 patients (78.6%) available for angiographic fo...Continue Reading

References

Jul 21, 2010·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·C J O'kellyT R Marotta
Jan 10, 2012·Journal of Neurosurgery·Ross C PufferGiuseppe Lanzino
Jan 17, 2013·Stroke; a Journal of Cerebral Circulation·Waleed BrinjikjiDavid F Kallmes
Jun 1, 2013·Stroke; a Journal of Cerebral Circulation·Nohra ChalouhiPascal Jabbour
Jul 18, 2014·Neurosurgery·Ajay K Wakhloo, Matthew J Gounis
Oct 31, 2014·AJNR. American Journal of Neuroradiology·D F KallmesP Lylyk
Feb 28, 2015·AJNR. American Journal of Neuroradiology·M A MöhlenbruchM Pham
May 20, 2015·Journal of Neurointerventional Surgery·Jai Jai Shiva ShankarAlain Weill
Jun 4, 2016·AJNR. American Journal of Neuroradiology·A M BurrowsG Lanzino
Jul 22, 2016·Journal of Neurointerventional Surgery·Francesco BrigantiFrancesco Maiuri
Sep 10, 2016·Interventional Neurology·David F KallmesElad Levy
Apr 26, 2017·World Neurosurgery·Pervinder BhogalMarta Aguilar Pérez

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Citations

Dec 16, 2019·Neurosurgery·Georgios A MaragkosVitor Mendes Pereira
Sep 10, 2020·Journal of Neurointerventional Surgery·Christian A TaschnerRené Chapot
Aug 11, 2019·Clinical Neuroradiology·S SirakovR Raychev
Jul 11, 2019·Stroke; a Journal of Cerebral Circulation·Felipe Padovani TrivelatoMarco Túlio Salles Rezende
Jan 26, 2021·Clinical Neuroradiology·Prasanth VelvaluriEckhard Quandt
Dec 8, 2019·World Neurosurgery·Christoph Wipplinger, Christoph J Griessenauer
Apr 24, 2021·Expert Review of Medical Devices·Prasanth VelvaluriJan-Bernd Hövener
Jun 11, 2021·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Andreas SimgenUmut Yilmaz
Apr 22, 2021·Journal of Neurosurgical Sciences·Mariangela PianoUNKNOWN Italian DERIVO® Registry Group

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