Safety and efficacy of the sleeve gastrectomy as a strategy towards kidney transplantation.

Surgical Endoscopy
Philippe BouchardAmin Andalib

Abstract

Obese individuals suffering from advanced chronic kidney disease (CKD) may be precluded from accessing kidney transplantation. Bariatric surgery is an effective treatment for obesity and related conditions but its use in those with severe CKD remains limited due to morbidity concerns. We aimed to evaluate the safety and efficacy of sleeve gastrectomy (SG) in patients with severe CKD as a bridging strategy towards kidney transplant candidacy. This is a single-center retrospective study of a prospectively collected database of obese patients referred by the multi-organ transplant team for surgical weight loss, who underwent SG during 2013-2018. The primary outcome was 90-day major morbidity. Secondary outcomes included weight loss, and successful kidney transplantation. Descriptive statistics are expressed as count (percent) or median (interquartile range). 32 patients met inclusion criteria. 18 (56%) were male with a median age and BMI of 51 (11) years and 42.3 (5.2) kg/m2, respectively. 29 (91%) patients were on dialysis for a median duration of 28 months before SG. Diabetes, hypertension, and dyslipidemia were present in 15 (47%), 25 (78%), and 21 (66%) patients, respectively. At 90 days after SG, there were no leaks, reoperat...Continue Reading

References

Oct 14, 2004·JAMA : the Journal of the American Medical Association·Henry BuchwaldKaren Schoelles
Dec 21, 2007·Journal of the American Society of Nephrology : JASN·Dorry L SegevRobert A Montgomery
Sep 3, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M TonelliJ Gill
Apr 1, 2014·Gynecologic Oncology·Kristy K WardSteven C Plaxe
Feb 25, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·C M FreemanT S Diwan
Mar 31, 2015·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Mohammad H JamalStacy A Brethauer
Jun 6, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Christopher J HillJennifer A McCaughan
Jun 22, 2015·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Stacy A BrethauerUNKNOWN ASMBS Clinical Issues Committee
Sep 30, 2015·Surgical Endoscopy·Amin AndalibStacy A Brethauer
Jan 19, 2016·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Mandeep R MehraUNKNOWN International Society for Heart Lung Transplantation (ISHLT) Heart Failure and Transplantation Council
Feb 16, 2017·The New England Journal of Medicine·Philip R SchauerUNKNOWN STAMPEDE Investigators
Mar 9, 2017·Canadian Journal of Kidney Health and Disease·Gabriel Chan, Mikael Soucisse
Jun 13, 2017·The New England Journal of Medicine·UNKNOWN GBD 2015 Obesity CollaboratorsChristopher J L Murray
Aug 10, 2017·Obesity Surgery·Tomasz DziodzioChristian Denecke
Sep 25, 2017·Annals of Surgery·Daniel P SchauerDavid E Arterburn
Mar 10, 2018·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Sandhya B KumarMatthew Y Lin
Mar 24, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Renana YeminiAndrei Keidar
Mar 24, 2018·JAMA : the Journal of the American Medical Association·Craig M HalesCynthia L Ogden
Aug 30, 2018·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Emanuele Lo MenzoAnn M Rogers
Feb 26, 2019·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rajiv SaranVahakn Shahinian

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Citations

Feb 7, 2021·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Amin AndalibOlivier Court
Feb 26, 2021·Transplant International : Official Journal of the European Society for Organ Transplantation·Roy HajjarGabriel Chan
Apr 28, 2021·Diabetes, Obesity & Metabolism·Richard SongPriya Sumithran
Oct 30, 2021·Current Opinion in Organ Transplantation·Hao Zhou, Stefan G Tullius

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