Safety and feasibility of biventricular devices reuse in general and elderly population--a single-center retrospective cohort study

Clinical Interventions in Aging
Raluca ŞoşdeanSorin Pescariu

Abstract

Cardiac resynchronization therapy (CRT) is known to have very important beneficial effects on heart failure patients. Unfortunately, biventricular implantable cardiac devices (CRT devices), through which this therapy is implemented, are very expensive and sometimes hard to achieve, especially in underdeveloped/developing economies, making this an important problem of public health. As a possible solution, CRT reuse is of great interest nowadays, but unlike simple devices, data in the literature are scarce about biventricular device reuse. To address safety concerns, we aimed to analyze infection burden in the general and elderly population and also early battery depletion and generator malfunction of resterilized biventricular devices compared to new devices. A cohort of 261 CRT patients (286 devices), who underwent implantation between 2000 and 2014, was retrospectively analyzed. The study group included 115 patients and 127 resterilized devices, that was divided into a subgroup of 69 elderly patients (≥60 years) and 74 devices and a subgroup of 47 younger patients (<60 years) and 53 devices, and the control group included 146 patients and 159 new devices. The groups were compared using a multivariate logistic regression model...Continue Reading

Citations

Nov 26, 2016·Cardiology Clinics·Michael Bestawros
May 7, 2020·The New England Journal of Medicine·Thomas F KhairyPaul Khairy
Feb 9, 2017·Heart Asia·Raja J SelvarajJayaraman Balachander
Dec 8, 2020·Pacing and Clinical Electrophysiology : PACE·Hisham RoshdyRadwa Elbelbesy
May 11, 2021·Expert Review of Medical Devices·Eliane Molina PsaltikidisKazuko Uchikawa Graziano

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