Safety and Feasibility of Laparoscopic Nephrectomy for Big Tumors (≥ 10 cm): A Retrospective Multicentric Study

Clinical Genitourinary Cancer
Grégory VerhoestKarim Bensalah

Abstract

Evaluate the feasibility of laparoscopic nephrectomy for big tumors. Data from 116 patients were retrospectively collected from 16 tertiary centres. Clinical and operative parameters, tumor characteristics, pre- and postoperative parameters, and renal function before and after surgery were analyzed. Mean age and body mass index were 61 years and 27.8 kg/m(2), respectively. Males represented 63.8% of patients, and 54.4% presented symptoms at diagnosis. Median tumor size was 11 cm, and 75% of the cases were performed by expert surgeons. Median operative time and blood loss were 180 minutes and 200 mL respectively. Conversion to open surgery was necessary in 20.7% of cases. Intraoperative complications related to massive hemorrhage occurred in 16.4% of patients, resulting in open conversion in 62.5%. Major postoperative complications occurred in only 10 patients (8.6%). In univariate analysis, intraoperative complications, age, and blood loss were predictive factors of conversion to open surgery. Positive surgical margins occurred in 6 patients (5.2%). None of them presented a local recurrence. Predictive factors of recurrence or progression were lymph node invasion, metastases, and Furhman grade. Laparoscopic nephrectomy for tumo...Continue Reading

References

Mar 26, 2004·European Urology·Jean-Jacques PatardBernard Lobel
Jan 31, 2006·European Urology·Antonio Lopez-BeltranZiya Kirkali
Apr 6, 2007·European Urology·Börje LjungbergUNKNOWN European Association of Urology Guideline Group for renal cell carcinoma
Jan 16, 2013·JSLS : Journal of the Society of Laparoendoscopic Surgeons·Grégory VerhoestKarim Bensalah

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Citations

Jan 20, 2018·Current Urology Reports·Georges Nasrallah, Fouad G Souki
Nov 22, 2019·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Ronney AbazaOscar Martinez
Oct 16, 2019·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·K BensalahA Méjean

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