Safety and feasibility of pulmonary artery pressure-guided heart failure therapy: rationale and design of the prospective CardioMEMS Monitoring Study for Heart Failure (MEMS-HF)

Clinical Research in Cardiology : Official Journal of the German Cardiac Society
C E AngermannMichael Böhm

Abstract

Wireless monitoring of pulmonary artery (PA) pressures with the CardioMEMS HF™ system is indicated in patients with New York Heart Association (NYHA) class III heart failure (HF). Randomized and observational trials have shown a reduction in HF-related hospitalizations and improved quality of life in patients using this device in the United States. MEMS-HF is a prospective, non-randomized, open-label, multicenter study to characterize safety and feasibility of using remote PA pressure monitoring in a real-world setting in Germany, The Netherlands and Ireland. After informed consent, adult patients with NYHA class III HF and a recent HF-related hospitalization are evaluated for suitability for permanent implantation of a CardioMEMS™ sensor. Participation in MEMS-HF is open to qualifying subjects regardless of left ventricular ejection fraction (LVEF). Patients with reduced ejection fraction must be on stable guideline-directed pharmacotherapy as tolerated. The study will enroll 230 patients in approximately 35 centers. Expected duration is 36 months (24-month enrolment plus ≥ 12-month follow-up). Primary endpoints are freedom from device/system-related complications and freedom from pressure sensor failure at 12-month post-impla...Continue Reading

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References

Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Apr 1, 2005·Psychotherapie, Psychosomatik, medizinische Psychologie·Hermann FallerChristiane E Angermann
Jul 24, 2007·American Heart Journal·Soko SetoguchiSebastian Schneeweiss
Feb 13, 2008·Archives of Internal Medicine·Tiny JaarsmaUNKNOWN Coordinating Study Evaluating Outcomes of Advising and Counseling in Heart Failure (COACH) Investigators
Mar 18, 2008·Journal of the American College of Cardiology·Robert C BourgeUNKNOWN COMPASS-HF Study Group
Oct 27, 2009·The American Journal of Medicine·Paul LeeJacqueline R Center
Jun 22, 2010·Circulation. Heart Failure·Lynne Warner StevensonRobert C Bourge
Nov 18, 2010·The New England Journal of Medicine·Sarwat I ChaudhryHarlan M Krumholz
Feb 15, 2011·Lancet·William T AbrahamUNKNOWN CHAMPION Trial Study Group
Feb 10, 2016·JAMA Internal Medicine·Michael K OngUNKNOWN Better Effectiveness After Transition–Heart Failure (BEAT-HF) Research Group
Mar 18, 2016·European Heart Journal·Michael BöhmUNKNOWN OptiLink HF Study Investigators
Mar 24, 2017·Journal of the American College of Cardiology·Akshay S DesaiJ Thomas Heywood
Jun 3, 2017·European Heart Journal·John M MorganMartin R Cowie
Jul 15, 2017·Journal of the American College of Cardiology·William T Abraham, Leor Perl
Jul 28, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Stefan StörkSven Klebs
Oct 7, 2017·Journal of the American College of Cardiology·Michael M GivertzUNKNOWN CHAMPION Trial Investigators
Oct 7, 2017·Journal of the American College of Cardiology·Liviu Klein

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Citations

Aug 2, 2018·BMC Cardiovascular Disorders·Carsten TschöpeFlorian Krackhardt
Oct 28, 2018·Nature Reviews. Cardiology·Magdi H Yacoub, Christopher McLeod
Dec 21, 2018·ESC Heart Failure·Elisabetta DinatoloMarco Metra
Feb 8, 2020·ESC Heart Failure·Martin R CowieUNKNOWN CardioMEMS Post-Market Study Investigators
Feb 11, 2020·Journal of Cardiovascular Medicine·Pietro Ameri, Christiane Angermann
Sep 25, 2020·Deutsche medizinische Wochenschrift·Tobias Daniel Trippel, Carsten Tschöpe
Dec 12, 2018·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·C G M J EurlingsH P Brunner-La Rocca
Feb 6, 2020·Herz·Gülmisal GüderChristiane E Angermann
Jan 8, 2020·European Heart Journal Supplements : Journal of the European Society of Cardiology·Maurizio VolterraniAndrew Js Coats
Jun 21, 2020·Current Cardiology Reports·Omaima AliJohn P Boehmer
May 8, 2020·Cardiac Failure Review·Ferdinando IellamoMaurizio Volterrani
Mar 16, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Johann Christoph GellerUNKNOWN IN-TIME Study Group
Jul 29, 2019·Current Cardiology Reports·Calvin C Leung
Sep 22, 2018·Der Internist·C E Angermann, S Rosenkranz
Jan 8, 2020·European Heart Journal Supplements : Journal of the European Society of Cardiology·Christiane E Angermann
Jun 6, 2020·Expert Review of Medical Devices·Muhammad Asif MangiGeorge V Moukarbel
Nov 21, 2019·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·J F Veenis, J J Brugts
May 8, 2020·Cardiac Failure Review·Ivo PlanincMaja Cikes
Sep 1, 2021·Herz·Jan WintrichMichael Böhm
Nov 30, 2021·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·Vera Vaz FerreiraRui Cruz Ferreira
Dec 30, 2021·JAMA Cardiology·Peter J KennelNir Uriel

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