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Safety and immunogenicity of an oral, inactivated, whole-cell vaccine for Shigella sonnei: preclinical studies and a Phase I trial

Vaccine

Aug 13, 2005

R McKenzieA L Bourgeois

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PubMed

Abstract

Orally delivered, inactivated whole-cell vaccines are safe methods of inducing local and systemic immunity. To increase surface proteins associated with adherence and invasion, Shigella sonnei were grown in BHI broth containing deoxycholate. A whole-cell vaccine (SsWC) was then produced...read more

Mentioned in this Paper

Vaccines, Inactivated
Shigella Vaccines
Formalin
Cavia
Vaccines
Dysentery, Bacillary
Formol
Fixatives
Shigella sonnei bacterium
Antibody Formation
33
Paper Details
References
  • References16
  • Citations31
12
  • References16
  • Citations31
1234

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Shigellosis

Shigellosis is an infection of the intestines caused by Shigella bacteria. Signs and symptoms may range from mild abdominal discomfort to full-blown dysentery characterized by cramps, diarrhea, with slimy-consistent stools, fever, blood, pus, or mucus in stools or tenesmus. Discover the latest research on shigellosis here.

Shigellosis

Shigellosis is an infection of the intestines caused by Shigella bacteria. Signs and symptoms may range from mild abdominal discomfort to full-blown dysentery characterized by cramps, diarrhea, with slimy-consistent stools, fever, blood, pus, or mucus in stools or tenesmus. Discover the latest research on shigellosis here.

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Safety and immunogenicity of an oral, inactivated, whole-cell vaccine for Shigella sonnei: preclinical studies and a Phase I trial

Vaccine

Aug 13, 2005

R McKenzieA L Bourgeois

PMID: 16095766

DOI: 10.1016/j.vaccine.2005.07.014

Abstract

Orally delivered, inactivated whole-cell vaccines are safe methods of inducing local and systemic immunity. To increase surface proteins associated with adherence and invasion, Shigella sonnei were grown in BHI broth containing deoxycholate. A whole-cell vaccine (SsWC) was then produced...read more

Mentioned in this Paper

Vaccines, Inactivated
Shigella Vaccines
Formalin
Cavia
Vaccines
Dysentery, Bacillary
Formol
Fixatives
Shigella sonnei bacterium
Antibody Formation
33

Feeds With Similar Papers

Shigellosis

Shigellosis is an infection of the intestines caused by Shigella bacteria. Signs and symptoms may range from mild abdominal discomfort to full-blown dysentery characterized by cramps, diarrhea, with slimy-consistent stools, fever, blood, pus, or mucus in stools or tenesmus. Discover the latest research on shigellosis here.

Shigellosis

Shigellosis is an infection of the intestines caused by Shigella bacteria. Signs and symptoms may range from mild abdominal discomfort to full-blown dysentery characterized by cramps, diarrhea, with slimy-consistent stools, fever, blood, pus, or mucus in stools or tenesmus. Discover the latest research on shigellosis here.

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Paper Details
References
  • References16
  • Citations31
12
  • References16
  • Citations31
1234

Download from

Publisher
PubMed
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