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Safety and immunogenicity of Shigella sonnei-CRM9 and Shigella flexneri type 2a-rEPAsucc conjugate vaccines in one- to four-year-old children

The Pediatric Infectious Disease Journal

Aug 13, 2003

Justen H PasswellIsrael Shigella Study Group

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PubMed

Abstract

Shigella conjugate vaccines have been shown to be safe, immunogenic and efficacious in adult volunteers. We have now investigated the safety and immunogenicity of investigational Shigella sonnei and Shigella flexneri 2a conjugate vaccines in 1- to 4-year-old children, the age group at g...read more

Mentioned in this Paper

Bacterial Proteins
Shigella Vaccines
Seroprevalence
Vaccines, Conjugate
Shigella sonnei bacterium
ToxA protein, Pseudomonas aeruginosa
Dysentery, Shigella Flexneri
Immunization Domain
Shigella
Disease Caused by Shigella Sonnei
24
Paper Details
References
  • References18
  • Citations37
12
  • References18
  • Citations37
1234

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Safety and immunogenicity of Shigella sonnei-CRM9 and Shigella flexneri type 2a-rEPAsucc conjugate vaccines in one- to four-year-old children

The Pediatric Infectious Disease Journal

Aug 13, 2003

Justen H PasswellIsrael Shigella Study Group

PMID: 12913770

DOI: 10.1097/01.inf.0000078156.03697.a5

Abstract

Shigella conjugate vaccines have been shown to be safe, immunogenic and efficacious in adult volunteers. We have now investigated the safety and immunogenicity of investigational Shigella sonnei and Shigella flexneri 2a conjugate vaccines in 1- to 4-year-old children, the age group at g...read more

Mentioned in this Paper

Bacterial Proteins
Shigella Vaccines
Seroprevalence
Vaccines, Conjugate
Shigella sonnei bacterium
ToxA protein, Pseudomonas aeruginosa
Dysentery, Shigella Flexneri
Immunization Domain
Shigella
Disease Caused by Shigella Sonnei
24

Feeds With Similar Papers

Diphtheria

Diphtheria is a bacterial infection caused by Corynebacterium diphtheriae. Transmission is usually airborne, and the disease usually presents with respiratory symptoms including sore throat and cough, but can involve complications such as myocarditis or neuritis. Find the latest research on diphtheria here.

Shigellosis

Shigellosis is an infection of the intestines caused by Shigella bacteria. Signs and symptoms may range from mild abdominal discomfort to full-blown dysentery characterized by cramps, diarrhea, with slimy-consistent stools, fever, blood, pus, or mucus in stools or tenesmus. Discover the latest research on shigellosis here.

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Expert Review of Vaccines

Inactivated and subunit vaccines to prevent shigellosis(opens in new tab)

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Paper Details
References
  • References18
  • Citations37
12
  • References18
  • Citations37
1234

Download from

Publisher
PubMed
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