Safety and supply of haemophilia products: worldwide perspectives

Haemophilia : the Official Journal of the World Federation of Hemophilia
Albert Farrugia

Abstract

The survival and well-being of people with haemophilia depends on the supply of safe therapeutic products. Safety and supply are entirely intertwined principles; in the absence of adequate amounts of coagulation products, safety measures may be compromised in order to enhance supply, leading to risks which may result in morbidity and mortality. As haemophilia therapy has emerged through the development of blood transfusion and plasma fractionation, the safety of the blood supply in general has had a strong effect on haemophilia care. Despite the gradual detachment of haemophilia care from blood transfusion through the use of recombinant products, the majority of the world's population with haemophilia in the developing world will be reliant on blood products for the foreseeable future. It is, therefore, important to continue efforts for a safe and sufficient blood supply worldwide. As such a blood supply develops, possibly in tandem with an independent plasma fractionation industry, the level of haemophilia care should improve with the gradual introduction of concentrates for the ultimate goal of covering all aspects of care. Constant vigilance for the threat of blood-borne pathogens should be linked to considerations of how th...Continue Reading

References

Nov 1, 1973·Vox Sanguinis·T W BarrowcliffeK M Dormandy
Jan 1, 1997·British Journal of Haematology·D M KeelingL M Williamson
Jan 5, 1999·Haemophilia : the Official Journal of the World Federation of Hemophilia·I R Walker, J A Julian
Dec 3, 1999·Haemophilia : the Official Journal of the World Federation of Hemophilia·B L EvattN De Bosch
Dec 3, 1999·Haemophilia : the Official Journal of the World Federation of Hemophilia·A Srivastava
May 3, 2000·Haemophilia : the Official Journal of the World Federation of Hemophilia·B L Evatt, L Robillard
Jun 9, 2001·The New England Journal of Medicine·P M Mannucci, E G Tuddenham
Sep 14, 2001·Haemophilia : the Official Journal of the World Federation of Hemophilia·K FischerH M van den Berg
Apr 16, 2002·Haemophilia : the Official Journal of the World Federation of Hemophilia·B L Evatt
May 16, 2002·Haemophilia : the Official Journal of the World Federation of Hemophilia·A Farrugia
May 16, 2002·Haemophilia : the Official Journal of the World Federation of Hemophilia·A Farrugia
Apr 16, 2003·Haemophilia : the Official Journal of the World Federation of Hemophilia·J S StonebrakerA J Nagle
Apr 16, 2003·Haemophilia : the Official Journal of the World Federation of Hemophilia·R A GruppoR J Navickis
Jul 23, 2003·Journal of Thrombosis and Haemostasis : JTH·E L SaenkoS W Pipe
Jul 3, 2004·Haemophilia : the Official Journal of the World Federation of Hemophilia·A Farrugia

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Citations

Oct 14, 2004·Haemophilia : the Official Journal of the World Federation of Hemophilia·A Farrugia
Dec 20, 2005·Vox Sanguinis·A-M Swärd-NilssonS Lethagen
Jan 16, 2008·Journal of Thrombosis and Haemostasis : JTH·S KnörH Kessler
Feb 9, 2011·Haemophilia : the Official Journal of the World Federation of Hemophilia·J S StonebrakerA Srivastava
Oct 23, 2009·Haemophilia : the Official Journal of the World Federation of Hemophilia·J S StonebrakerM Brooker
Oct 23, 2009·Haemophilia : the Official Journal of the World Federation of Hemophilia·J S StonebrakerA Srivastava
May 9, 2014·Haemophilia : the Official Journal of the World Federation of Hemophilia·J McCueD Euwart
Jun 22, 2015·Biologicals : Journal of the International Association of Biological Standardization·Justin McCueHeidi Reichert
Jul 5, 2008·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Javier BatlleCarlos Aguilar

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