PMID: 16612902Apr 15, 2006Paper

Safety evaluation for a biodiesel process using prion-contaminated animal fat as a source

Environmental Science and Pollution Research International
Björn SeidelAndreas Schäffer

Abstract

Due to the bovine spongiform encephalopathy (BSE), specified risk material (SRM) as well as animal meat and bone meal (MBM) are banned from the food and feed chain because of a possible infection with pathogenic prions (PrP(Sc)). Nowadays, prions are widely accepted to be responsible for TSE(transmissible spongiform encephalopathies)-caused illnesses like BSE and scrapie, and especially for the occurrence of the new variant of CJD in humans. Presently, SRM and MBM are burnt under high temperatures to avoid any hazards for humans, animals or the environment. The aim of this study was to evaluate a method using animal fat separated from Category I material which includes SRM and the carcasses of TSE-infected animals, or animals suspected of being infected with TSE, as a source for producing biodiesel by transesterification, analogous to the biodiesel process using vegetable oil. For this purpose, animal fat was spiked with scrapie-infected hamster brain equivalents--as representative for a TSE-infected animal--and the biodiesel manufacturing process was downscaled and performed under lab-scale conditions. The results analysed by Western blotting showed clearly that almost each single step of the process leads to a significant red...Continue Reading

Citations

Apr 26, 2008·Environmental Science and Pollution Research International·Yoichi NoyaKoh-ichi Seki
Aug 14, 2008·PloS One·Cathrin E BruederleJohn Mark Carter
Jun 27, 2009·Environmental Science and Pollution Research International·Koh-ichi SekiKazue Ohkura

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