PMID: 9420757Jan 1, 1995Paper

Safety of dipyridamole testing in 73,806 patients: the Multicenter Dipyridamole Safety Study

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
J LetteS Nattel

Abstract

Dipyridamole imaging is widely used as an alternative to exercise testing to identify and risk stratify patients with coronary artery disease. Safety data on intravenous dipyridamole stress testing has been derived largely from individual institutional data. Data were collected retrospectively by 85 coinvestigators from 73,806 patients who underwent intravenous dipyridamole stress imaging in 59 hospitals and 19 countries to determine the incidence of major adverse reactions during testing. The dose of dipyridamole infused was 0.56 mg/kg in 64,740 patients, 0.74 mg/kg in 6551 patients, and 0.84 mg/kg in 2515 patients. Combined major adverse events among the entire 73,806 patients included seven cardiac deaths (0.95 per 10,000), 13 nonfatal myocardial infarctions (1.76 per 10,000), six nonfatal sustained ventricular arrhythmias (0.81 per 10,000) (ventricular tachycardia in two and ventricular fibrillation in four), nine transient cerebral ischemic attacks (1.22 per 10,000), (with speech or motor deficit), one stroke, and nine severe bronchospasms (1.22 per 10,000) (one intubation and eight near intubations). In addition to the safety data, detailed demographic, peripheral hemodynamic, side effect, and concomitant drug data were e...Continue Reading

References

Dec 1, 1992·International Journal of Cardiology·F ArrigoG Quattrocchi
Feb 15, 1992·The American Journal of Cardiology·F S VillanuevaG A Beller
Feb 15, 1992·The American Journal of Cardiology·H O KleinS Gilboa
Jul 1, 1990·Chest·J J Houben
Jan 1, 1990·European Journal of Nuclear Medicine·A H KwaiD E Tow
Feb 15, 1989·The American Journal of Cardiology·E PicanoA L'Abbate
Jul 26, 1986·British Medical Journal·C SylvénR Brandt
Dec 15, 1988·Annals of Internal Medicine·H Z FriedmanW W O'Neill
Jan 1, 1988·The American Journal of Cardiology·J D Pearlman, C A Boucher
Mar 1, 1988·Journal of the American College of Cardiology·J Y LamL Samuels
May 1, 1988·Chest·M S Blumenthal, C S McCauley
Mar 1, 1987·International Journal of Cardiology·G J LaarmanC A Ascoop
Jan 1, 1983·Journal of Neurosurgery·N F KassellJ A Sprowell
Nov 1, 1982·Stroke; a Journal of Cerebral Circulation·D J BoariniJ A Sprowell
Jan 1, 1981·European Journal of Nuclear Medicine·J L DemangeatR Voegtlin
Feb 1, 1994·Journal of the American College of Cardiology·M D CerqueiraA S Iskandrian
Feb 1, 1994·Journal of the American College of Cardiology·D D Miller, A J Labovitz
Feb 1, 1994·Journal of the American College of Cardiology·M A Creager, S J Creager
Jun 1, 1993·The American Journal of Cardiology·D J PennellP J Ell
Jan 1, 1994·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·A S IskandrianJ Heo

❮ Previous
Next ❯

Citations

May 8, 2004·European Journal of Nuclear Medicine and Molecular Imaging·S R UnderwoodUNKNOWN Royal College of Radiologists
Jun 30, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Levent A GunerMustafa Unlu
Mar 7, 2009·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Andrew J YoonMark I Travin
Feb 14, 2012·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·E Gordon DepueyL Samuel Wann
Jun 10, 2005·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Fahim H JafaryNasiruddin Ahmed
Dec 19, 2006·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Milena J HenzlovaUNKNOWN Quality Assurance Committee of the American Society of Nuclear Cardiology
Nov 21, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Halil Mutlu, Jeffrey Leppo
Mar 29, 2008·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Andrea De Lorenzo, Ronaldo S L Lima
Sep 2, 2008·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·James R JohnsonStephen A Jenkins
Sep 2, 1998·The American Journal of Cardiology·A R ShehataG V Heller
Nov 13, 2002·Journal of the American College of Cardiology·Laurent M RiouDavid K Glover
Mar 1, 1997·Journal of the American College of Cardiology·J Candell-RieraJ Soler-Soler
Sep 1, 1996·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·H A DakikM S Verani
Nov 1, 1996·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·M D Cerqueira
Nov 1, 1996·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·J A Leppo
Dec 23, 1999·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·A HashimotoT Yasuda
Dec 23, 1999·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·M P White
May 15, 2002·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Farhood SaremiMichael E Siegel
Jun 13, 2013·Pharmacology & Therapeutics·Hoshang Farhad, Venkatesh L Murthy
Mar 15, 2014·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Li-Fan LinDaniel H Y Shen
Oct 12, 2010·Annals of Nuclear Medicine·Ronaldo de Souza Leão LimaAndrea De Lorenzo
Nov 22, 2011·Revue des maladies respiratoires·C Sanfiorenzo, A Pipet
Jun 19, 2014·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Fadi G Hage
May 24, 2005·European Journal of Nuclear Medicine and Molecular Imaging·B HesseUNKNOWN EANM/ESC Group
Dec 21, 2002·Current Cardiology Reports·Sachin M NavareGary V Heller
Feb 19, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Rami Doukky, Yasmeen Golzar
Jun 26, 2015·European Heart Journal Cardiovascular Imaging·Jose V Monmeneu MenadasAlicia Maceira Gonzalez
Feb 5, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Rajeeve Subbiah, Pravin V Patil
Feb 24, 2016·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Mridula RaiW Lane Duvall
Mar 9, 2013·Pharmacotherapy·Sachil ShahRobert S Rosenstein
Mar 17, 2001·Current Problems in Cardiology·D S BermanG Germano
Apr 4, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Piotr LipiecJarosław D Kasprzak
Feb 18, 2004·Revista española de cardiología·Oscar Díaz-CastroJavier Goicolea
May 16, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Vasken DilsizianRonald G Schwartz
Aug 24, 1999·Cardiology Clinics·E PicanoA Varga
Oct 6, 2001·Radiologic Clinics of North America·M D Cerqueira, A Lawrence

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Bradyarrhythmias

Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.

Related Papers

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
R TailleferM Jarry
Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
H A DakikM S Verani
Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
M G TreuthM S Verani
© 2021 Meta ULC. All rights reserved