Safety of Endoscopic Resection for Upper Gastrointestinal Subepithelial Tumors Originating from the Muscularis Propria Layer: An Analysis of 733 Tumors

The American Journal of Gastroenterology
Li-ping YeLin-hong Zhu

Abstract

Although endoscopic resection is an accepted technique for upper gastrointestinal subepithelial tumors (SETs) originating from the muscularis propria (MP) layer, published data regarding its complications are highly variable and limited to small data series. This study aimed to analyze the safety of endoscopic resection in a large case series. A total of 726 consecutive patients with 733 upper gastrointestinal SETs originating from the MP layer underwent endoscopic resection from June 2005 to December 2014. The complete resection rate, perioperative perforation rate, and perioperative bleeding rate were the main outcome measurements. The complete resection rate was 97.1%. Ninety-four patients had complications (12.9%), including 88 with perioperative perforations (12.1%), 13 with perioperative bleeding (1.8%), 5 with localized peritonitis (0.7%), and one with delayed bleeding (0.1%). Eleven patients required surgery; the others were treated endoscopically. Risk factors for incomplete resection were extensive connection of the tumor to the MP layer (P=0.007) and extraluminal growth (P=0.048). Risk factors for perioperative perforation were larger tumor size (≤2.0 cm vs. 2.1-3.0 cm vs. >3.0 cm, P=0.021), extraluminal growth (P=0....Continue Reading

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Citations

Aug 25, 2016·Surgical Endoscopy·Tae Wook KimGeun Am Song
Jan 14, 2020·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·D M LiY P Jiang
Mar 20, 2020·Surgical Endoscopy·Shou-Jiang TangShengyu Zhang
Mar 12, 2021·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Osamu GotoKatsuhiko Iwakiri
Aug 28, 2021·Endoscopy International Open·Hiromu FukudaSatoki Shichijo

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