Safety of Gastrointestinal Endoscopy With Conscious Sedation in Patients With and Without Obstructive Sleep Apnea

Journal of Clinical Gastroenterology
Christian M AndradeGitanjali Vidyarthi

Abstract

Patients with obstructive sleep apnea (OSA) undergoing endoscopy with sedation are considered by practitioners to be at a higher risk for cardiopulmonary complications. The aim of the present study was to evaluate the safety of conscious sedation in patients with OSA undergoing gastrointestinal endoscopy. This is an IRB-approved prospective cohort study performed at the James A. Haley VA. A total of 248 patients with confirmed moderate or severe OSA by polysomnography and 252 patients without OSA were enrolled. Cardiopulmonary variables such as heart rate, blood pressure, and level of blood oxygen saturation were recorded at 3-minute intervals throughout the endoscopic procedure. In total, 302 colonoscopies, 119 esophagogastroduodenoscopies, 6 flexible sigmoidoscopies, and 60 esophagogastroduodenoscopy/colonoscopies were performed. None of the patients in the study required endotracheal intubation, pharmacologic reversal, or experienced an adverse outcome as a result of changes in blood pressure, heart rate, or blood oxygen saturation. There were no significant differences in the rate of tachycardia (P=0.749), bradycardia (P=0.438), hypotension (systolic/diastolic, P=0.460; mean arterial pressure, P=0.571), or hypoxia (P=0.787)...Continue Reading

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Citations

May 17, 2017·Current Opinion in Anaesthesiology·Megan L Allen
Dec 1, 2017·World Journal of Gastrointestinal Endoscopy·Christian M AndradeGitanjali Vidyarthi
May 31, 2018·Current Opinion in Anaesthesiology·Kate Leslie, James Sgroi
Sep 22, 2019·International Journal of Environmental Research and Public Health·Ryuma UrahamaHisahiro Matsubara
Jan 22, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Shabnam GhazizadehAbie H Mendelsohn
Sep 16, 2017·Current Opinion in Anaesthesiology·Kate Leslie, Benjamin Kave
Sep 4, 2019·Journal of Bronchology & Interventional Pulmonology·Anna M MayKingman P Strohl
Jun 7, 2019·Tuberculosis and Respiratory Diseases·Jaeyoung ChoJinwoo Lee
Mar 24, 2016·Current Treatment Options in Gastroenterology·Katherine B HaganJohn Vargo
Feb 11, 2021·Current Medical Research and Opinion·Richard M PinoLuca M Bigatello

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Methods Mentioned

BETA
sedation

Software Mentioned

SPSS

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