Safety of moderate-to-deep sedation performed by sedation practitioners: A national prospective observational study

European Journal of Anaesthesiology
Lena KoersBenedikt Preckel

Abstract

In the Netherlands, a significant proportion of moderate-to-deep sedation is performed by sedation practitioners under the indirect supervision of an anaesthesiologist but there are limited safety data available. To estimate the rate of sedation-related adverse events and patient relevant outcomes (PRO). This was a prospective national observational study. Data were collected with a modified adverse event reporting tool from the International Sedation Task Force of the World Society of Intravenous Anaesthesia. A total of 24 hospitals in the Netherlands where moderate-to-deep sedation was performed by sedation practitioners from the 1 February 2015 to 1 March 2016. Consecutive adults undergoing moderate-to-deep sedation for gastrointestinal, pulmonary and cardiac procedures. Observation: Analysis included descriptive statistics and a multivariate logistic regression model for an association between adverse events and PRO. The primary outcome was the rate of unfavourable PRO (admission to ICU, permanent neurological deficit, pulmonary aspiration or death). Secondary outcome was the rate of moderate-to-good PRO (unplanned hospital admission or escalation of care). Composite outcome was the sum of all primary and secondary outcomes...Continue Reading

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Citations

Mar 1, 2019·European Journal of Anaesthesiology·Massimo LampertiRobert Fitzgerald
Aug 8, 2019·Current Opinion in Anaesthesiology·Maartje van HaperenSusanne Eberl
Mar 10, 2021·Expert Review of Clinical Pharmacology·Weiyun ChenYuguang Huang
Apr 22, 2021·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Eva P C van SchaikWillem-Jan M Schellekens

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