Safety of Pregnancy After Cerebral Venous Thrombosis: A Systematic Review

Stroke; a Journal of Cerebral Circulation
Diana Aguiar de SousaJosé M Ferro

Abstract

Pregnancy and puerperium are associated with an increased risk of venous thrombotic events (VTEs), including cerebral venous thrombosis (CVT). We aimed to systematically review, in pregnant woman with previous CVT, (1) the risk of recurrence of CVT or other VTE; (2) the result of pregnancy; and (3) the association of antithrombotic prophylaxis with these outcomes. We searched MEDLINE, Cochrane Database of Systematic Reviews, clinicaltrials.gov (from inception to July 2015), and reference lists of included studies and review articles. We considered observational studies reporting original data on the frequency of CVT or other VTE associated with pregnancy or puerperium in women with history of CVT. Thirteen studies were included. A simple pooled analysis of individual patient data and meta-analysis of proportions using a random effect model were performed. (1) 1 CVT recurrences/217 pregnancies (9 per 1000; 95% confidence interval, 3-33) and 5 noncerebral VTE/186 pregnancies (27 per 1000; 95% confidence interval, 12-61). (2) Pregnancy outcome: 33 spontaneous abortions/186 pregnancies (17.7%; 95% confidence interval, 13-24). (3) Data on the risk of CVT/extracerebral VTE according to antithrombotic prophylaxis was limited. Miscarri...Continue Reading

References

Nov 5, 1999·Human Reproduction·S A BrighamR G Farquharson
Nov 18, 2000·The New England Journal of Medicine·P Brill-EdwardsUNKNOWN Recurrence of Clot in This Pregnancy Study Group
Jan 23, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Zarko AlfirevicVanessa Martlew
May 16, 2002·Cerebrovascular Diseases·J M FerroUNKNOWN Cerebral Venous Thrombosis Portugese Collaborative Study Group
May 20, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·S MehraeinF Masuhr
Feb 21, 2004·Stroke; a Journal of Cerebral Circulation·José M FerroUNKNOWN ISCVT Investigators
Feb 15, 2005·Clinical Neurology and Neurosurgery·Erwin StolzManfred Kaps
May 5, 2005·Journal of Thrombosis and Haemostasis : JTH·I PabingerK Lechner
Jul 19, 2005·Clinical Neurology and Neurosurgery·Simone AppenzellerFernando Cendes
Jan 19, 2006·Seminars in Reproductive Medicine·William H Kutteh, Douglas A Triplett
May 2, 2006·American Journal of Obstetrics and Gynecology·Andra H JamesEvan R Myers
Sep 21, 2006·British Journal of Haematology·Valerio De StefanoGiuseppe Leone
Oct 14, 2006·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C-C LiangT-H Lee
Jun 16, 2010·Circulation·Ida MartinelliPier Mannuccio Mannucci
Dec 15, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C Cantu-BritoJ F Baizabal-Carvallo
Jan 7, 2011·Journal of Clinical Epidemiology·Howard BalshemGordon H Guyatt
Jun 5, 2013·Journal of the American Statistical Association·Dulal K BhaumikRobert D Gibbons
Aug 8, 2013·Cerebrovascular Diseases·Jonathan CironJean-Philippe Neau
Sep 14, 2013·La Revue de médecine interne·O PourratF Pierre
Feb 3, 2015·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·A Cruz-HerranzE Díez-Tejedor

❮ Previous
Next ❯

Citations

Feb 24, 2017·Stroke; a Journal of Cerebral Circulation·Ava L LibermanBabak B Navi
Oct 5, 2017·Stroke; a Journal of Cerebral Circulation·Diana Aguiar de SousaUNKNOWN ISCVT-2-PREGNANCY Investigators
Feb 14, 2019·Der Nervenarzt·Christian WeimarTobias Kurth
Apr 18, 2019·VASA. Zeitschrift für Gefässkrankheiten·Hans-Christian Koennecke
Aug 19, 2017·Nature Reviews. Neurology·Suzanne M SilvisJonathan M Coutinho
Jul 22, 2017·Nature Reviews. Neurology·Charlotte CordonnierUNKNOWN Women Initiative for Stroke in Europe (WISE) group
Apr 11, 2019·Obstetrics and Gynecology·Luis D PachecoGeorge R Saade
May 28, 2019·Anesthesia and Analgesia·Eliza C Miller, Lisa Leffert
Oct 28, 2019·Journal of Thrombosis and Thrombolysis·Amihai RottenstreichYosef Kalish
Sep 7, 2016·Journal of Thrombosis and Haemostasis : JTH·I MartinelliF Peyvandi
Dec 4, 2016·Hematology·Kelley McLean, Mary Cushman
Aug 24, 2019·Current Neurology and Neuroscience Reports·José M Ferro, Diana Aguiar de Sousa
May 28, 2016·Current Neurology and Neuroscience Reports·H Steven Block
Aug 24, 2017·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J M FerroUNKNOWN European Stroke Organization
Nov 15, 2017·Journal of Neurology·Diana Aguiar de SousaJosé M Ferro
May 10, 2019·Acta neurochirurgica·Ifigeneia GiotiMoses-Akis Lambrou
Jun 4, 2019·Frontiers in Neurology·Raghunath AvanaliNagesh C Shanbhag
Jul 22, 2017·Internal and Emergency Medicine·Francesco DentaliMarco Cei
Feb 16, 2021·Hämostaseologie·Diana Aguiar de Sousa
Feb 16, 2021·Circulation·Islam Y ElgendyUNKNOWN American College of Cardiology Cardiovascular Disease in Women Committee
Mar 2, 2021·Revue neurologique·M YgerS Alamowitch
Mar 23, 2021·Therapeutic Advances in Neurological Disorders·Büșra DurmușSusanna M Zuurbier
Apr 16, 2021·Fortschritte der Neurologie-Psychiatrie·Christian Weimar
Jan 26, 2020·Clinical Radiology·A GhoneimR Jampana
Oct 18, 2016·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Nicole S Carlson
Nov 21, 2017·Gynécologie, Obstétrique, Fertilité & Sénologie·H Cohen, M Rossignol

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved