Abstract
There are no published data on the safety of cardiopulmonary exercise testing in patients with aortic stenosis. In this retrospective descriptive study, we examined 347 consecutive patients with aortic stenosis who underwent cardiopulmonary exercise testing at a tertiary referral center. We recorded major events including death, nonfatal major events (cardiac arrest, symptomatic or sustained ventricular or supraventricular tachycardia, myocardial infarction, and syncope), and minor events such as hypotension, nonsustained supraventricular and ventricular arrhythmias, positive electrocardiographic changes, and angina. Of 347 patients, 65 (19%) had mild, 145 (42%) had moderate, and 137 (40%) had severe aortic stenosis by echocardiographic criteria. No major events occurred during the tests. Minor events occurred in a total of 97 patients (28%), including 10 patients who developed supraventricular arrhythmias without hypotension; and one who had asymptomatic nonsustained ventricular tachycardia. Symptom-limited cardiopulmonary exercise testing in cardiology-referred patients with aortic stenosis with preserved systolic function appears to be associated with very low risk of major adverse cardiovascular events during testing.
References
Apr 1, 1990·Journal of the American College of Cardiology·P A PellikkaA J Tajik
Dec 15, 1995·Circulation·M R CostanzoE Rose
Jul 1, 1997·Circulation·R J GibbonsT J Ryan
Aug 24, 1999·Journal of Cardiopulmonary Rehabilitation·R W SquiresG T Gau
Sep 15, 2000·Journal of the American College of Cardiology·S SharmaW J McKenna
Sep 27, 2000·Circulation·J L FlegT Bazzarre
Sep 18, 2001·Heart·M C AmatoJ A Ramires
Dec 18, 2001·International Journal of Cardiology·S TakedaJ Chambers
Oct 24, 2002·Journal of the American College of Cardiology·Raymond J GibbonsUNKNOWN American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Committee to Update the 1997 Ex
Jul 28, 2004·Circulation·Richard V MilaniMandeep R Mehra
Apr 12, 2005·European Heart Journal·Paul DasJohn Chambers
Nov 23, 2006·Cardiology·Roberto PeidroArnaldo Angelino
Sep 27, 2007·Echocardiography·Sylvestre MaréchauxGhislaine Deklunder
Feb 24, 2009·Lancet·Blase A Carabello, Walter J Paulus
Jun 23, 2009·The American Journal of Cardiology·Bilal AijazThomas G Allison
Jan 6, 2010·European Heart Journal·Alec Vahanian, Catherine M Otto
Apr 21, 2010·The American Journal of Cardiology·Amanda MethvinJaved Butler
Citations
Jun 19, 2014·The Journal of Thoracic and Cardiovascular Surgery·Rick A NishimuraClyde W Yancy
Sep 23, 2014·Archives of Cardiovascular Diseases·Franck LevyChristophe Tribouilloy
Mar 8, 2014·Journal of the American College of Cardiology·Rick A NishimuraJames D Thomas
Mar 25, 2014·Journal of the American College of Cardiology·Marie-Annick ClavelMaurice Enriquez-Sarano
Apr 23, 2016·Journal of the American College of Cardiology·Alberto Dominguez-Rodriguez, Pedro Abreu-Gonzalez
Apr 5, 2014·The American Journal of Cardiology·Abhijeet DhobleThomas G Allison
Aug 10, 2016·American Heart Journal·Alberto Dominguez-Rodriguez, Pedro Abreu-Gonzalez
Aug 10, 2016·American Heart Journal·Marko BanovicSvetozar Putnik
May 2, 2014·European Journal of Preventive Cardiology·Frank BeutnerStephan Gielen
Apr 11, 2017·Cardiology·James L Gentry IiiBrian P Griffin
Dec 2, 2015·Seminars in Cardiothoracic and Vascular Anesthesia·George Silvay, Zdravka Zafirova
Apr 14, 2018·Journal of the American Heart Association·Chetan P HudedMilind Y Desai
May 17, 2017·Circulation·Björn RedforsPhilippe Généreux
Mar 5, 2014·Circulation·Rick A NishimuraJames D Thomas
Jul 14, 2016·Circulation. Cardiovascular Imaging·Ahmad MasriMilind Y Desai
Jul 11, 2019·Journal of Medical Ultrasonics·Kenya Kusunose
Feb 11, 2015·Expert Review of Cardiovascular Therapy·Peyman NajiMilind Y Desai
Dec 22, 2020·Journal of the American College of Cardiology·UNKNOWN Writing Committee MembersChristopher Toly
Dec 18, 2020·Circulation·Catherine M OttoChristopher Toly
May 12, 2021·The Journal of Thoracic and Cardiovascular Surgery·UNKNOWN Writing Committee MembersY Joseph Woo