Sagittal Abdominal Diameter, Waist Circumference, and BMI as Predictors of Multiple Measures of Glucose Metabolism: An NHANES Investigation of US Adults

Journal of Diabetes Research
Shelby A FirouziBruce W Bailey

Abstract

The objective was to compare associations between sagittal abdominal diameter (SAD), waist circumference, and BMI to the oral glucose tolerance test (OGTT), along with fasting glucose, HbA1c, and HOMA-IR, in a nationally representative sample of 3582 US adults. The study also analyzed the effect of multiple covariates on the anthropometric and glucose metabolism associations. A cross-sectional design was used. SAD was assessed using an abdominal caliper. All other data were collected following strict NHANES protocols. The OGTT was the primary variable used to index glucose metabolism. Fasting glucose, HbA1c, and HOMA-IR were also evaluated. Results showed that mean ± SE values were as follows: SAD: 22.3 ± 0.1 cm, waist circumference: 98.0 ± 0.4 cm, BMI: 28.6 ± 0.2 kg/m2, OGTT: 113.9 ± 1.0 mg/dL, fasting glucose: 99.6 ± 0.3 mg/dL, HbA1c: 5.4 ± 0.01%, and HOMA-IR: 3.2 ± 0.1. Compared to waist circumference and BMI, SAD consistently emerged as the best predictor of glucose metabolism, before and after adjusting for the covariates, and with the sample stratified by gender, race, or age. SAD was not a better predictor of OGTT among normal-weight adults or non-Hispanic Black adults. Due to the ease of taking SAD measurements, we reco...Continue Reading

References

May 1, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·P RissanenM Uusitupa
Aug 22, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·E TurcatoM Zamboni
May 27, 2004·Diabetes Care·Tara M WallaceDavid R Matthews
Aug 21, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J StevensK P Truesdale
Jun 5, 2012·QJM : Monthly Journal of the Association of Physicians·R Lee, T A Chowdhury
Sep 11, 2012·Diabetes Care·Pia PajunenPaul Knekt
Jul 17, 2013·Journal of Diabetes and Metabolic Disorders·Natalia Cavalheri de Souza, Erick Prado de Oliveira
Dec 5, 2014·PharmacoEconomics·Adela Hruby, Frank B Hu
Dec 20, 2014·Journal of Obesity·Jane J LeeJeanne H Freeland-Graves
Dec 30, 2014·Diabetes Care·UNKNOWN American Diabetes Association
Aug 25, 2015·The American Journal of Medicine·Henry S Kahn, Kai McKeever Bullard
Oct 3, 2015·Der Internist·P E H Schwarz

❮ Previous
Next ❯

Citations

Nov 27, 2019·JAAPA : Official Journal of the American Academy of Physician Assistants·Dan Tzizik
May 27, 2020·Journal of Diabetes Research·McKayla J NiemannLance E Davidson
Nov 24, 2020·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Grith MøllerMads Vendelbo Lind
Dec 31, 2020·Journal of Obesity·James R FowlerJames D LeCheminant
Oct 9, 2021·Journal of Cancer Education : the Official Journal of the American Association for Cancer Education·Roy ValenzuelaJennifer J Salinas

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray
blood draw

Software Mentioned

SurveyMeans
Proc SurveyReg
SurveyFreq
SAS
Proc

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.