Sagittal zonal organization of climbing fibre input to the cerebellar anterior lobe of the ferret

Experimental Brain Research
M Garwicz

Abstract

The organization of climbing fibre input to the cerebellar anterior lobe of the ferret was investigated in barbiturate-anaesthetized animals. Climbing fibre field potentials evoked on electrical stimulation of forelimb and hindlimb nerves were recorded at the cerebellar surface. Based on characteristic latencies of climbing fibre responses and their relative localization along the longitudinal axis of the folia, nine sagittally oriented zones could be distinguished and were tentatively named, from medial to lateral, A, X, B, C1, Cx, C2, C3, D1 and D2. Within the C1, C2 and C3 zones, climbing fibre input from the ipsilateral forelimb was found caudally and from the hindlimb rostrally, while the corresponding topographical representation in the B and D2 zones was medial to lateral. The X, Cx and D1 zones did not receive input from the hindlimb, while input from the forelimb to the A zone was weak. Overall, the sagittal zonal organization of climbing fibre input appears to conform with the compartmentalization of the ferret cerebellum based on the myeloarchitecture of corticonuclear fibres, although the X and Cx zones have not been previously identified. In terms of both general electrophysiological characteristics of input to dif...Continue Reading

Citations

Sep 1, 2005·Experimental Brain Research·P SvenssonG Hesslow
Jan 5, 2000·Neuroreport·M RijntjesC Weiller
Jan 1, 1997·Annual Review of Neuroscience·K Herrup, B Kuemerle
Aug 21, 2010·The Journal of Physiology·Laurens W J BosmanChris I De Zeeuw
Oct 1, 2005·The Journal of Comparative Neurology·Angelique PijpersTom J H Ruigrok
Sep 27, 2003·The European Journal of Neuroscience·Antonia L EdgeRichard Apps
Oct 16, 2008·The Journal of Comparative Neurology·Franziska NeudertChristoph Redies
Feb 22, 2007·The Journal of Comparative Neurology·Maria ChristenssonMartin Garwicz
Aug 21, 2014·Frontiers in Neural Circuits·Anders RasmussenGermund Hesslow
Jul 31, 2019·Human Brain Mapping·Reiko AshidaJonathan C W Brooks
Jul 7, 2007·Journal of Neurophysiology·Fredrik Bengtsson, Henrik Jörntell

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