(Salen)chromium(III)/DMAP: an efficient catalyst system for the selective synthesis of 5-substituted oxazolidinones from carbon dioxide and aziridines

Organic Letters
Aaron W Miller, SonBinh T Nguyen

Abstract

[reaction: see text] (Salen)chromium(III)/DMAP was found to be an active catalyst system for the coupling of CO(2) and aziridines. The oxazolidinone products were produced in high yield and selectivity from the opening of the aziridine at the most substituted N-C bond. This catalyst system worked well for a wide variety of monosubstituted N-aryl and N-alkyl aziridines as well as a 2,3-disubstituted N-alkyl aziridine.

References

Nov 15, 2001·Journal of the American Chemical Society·R L Paddock, S B Nguyen
Aug 6, 2002·The Journal of Antimicrobial Chemotherapy·A C FluitD Milatovic
Jan 17, 2003·Annals of Internal Medicine·Robert C Moellering
Apr 12, 2003·The Journal of Biological Chemistry·Jerry R ColcaAlexander S Mankin
May 23, 2003·Antimicrobial Agents and Chemotherapy·Ethan RubinsteinJack Remington
Jul 2, 2005·Expert Opinion on Emerging Drugs·G W Kaatz, M J Rybak

❮ Previous
Next ❯

Citations

Feb 20, 2016·Angewandte Chemie·Jeroen RintjemaArjan W Kleij
Jun 7, 2014·Chemistry : a European Journal·Teemu NiemiTimo Repo
Aug 18, 2005·Chemistry : a European Journal·Gerrit A LuinstraBernhard Rieger
Oct 23, 2014·Chemical Communications : Chem Comm·Robert L PaddockSonBinh T Nguyen
Jun 12, 2008·Chemical Reviews·Marcos A P MartinsHelio G Bonacorso
Jun 15, 2007·Chemical Reviews·Toshiyasu SakakuraHiroyuki Yasuda
Jun 8, 2011·Organic Letters·Francesco FontanaVarinder K Aggarwal
Sep 17, 2014·Chemical Reviews·Marcos A P MartinsHelio G Bonacorso
Jan 17, 2019·The Journal of Organic Chemistry·Yueqin XieYingming Yao

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.