Saline cathartics and the adsorptive capacity of activated charcoal for aspirin

Annals of Emergency Medicine
P A Czajka, J D Konrad


The influence of three saline cathartics and tap water on the adsorption characteristics of activated charcoal for aspirin was studied with adsorption isotherms. Compared with distilled water, the adsorptive capacity of activated charcoal for aspirin was not significantly altered by magnesium sulfate, sodium sulfate, or tap water. Pretreating activated charcoal with magnesium citrate reduced the adsorptive capacity of activated charcoal by 15% (P less than .05). There was no significant correlation between mean pH values and adsorptive capacities in all test solutions. None of the saline cathartic solutions apparently displaced aspirin that already was adsorbed by activated charcoal.


Jan 1, 1981·Annals of Emergency Medicine·A R Soslow
Jan 1, 1982·Journal of Clinical Pharmacology·I S SketrisD T Stafford
May 1, 1981·Annals of Emergency Medicine·J M Riegel, C E Becker
Feb 23, 1981·Archives of Internal Medicine·A R Temple


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Apr 13, 2005·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·P A ChykaEuropean Association of Poisons Centres and Clinical Toxicologists
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