PMID: 12769995May 29, 2003Paper

Saliva secretion and ionic composition of saliva in the cockroach Periplaneta americana after serotonin and dopamine stimulation, and effects of ouabain and bumetamide

Journal of Insect Physiology
K RietdorfB Walz

Abstract

Isolated salivary glands of Periplaneta americana were used to measure secretion rates and, by quantitative capillary electrophoresis, Na(+), K(+), and Cl(-) concentrations in saliva collected during dopamine (1 micro M) and serotonin (1 micro M) stimulation in the absence and presence of ouabain (100 micro M) or bumetanide (10 micro M). Dopamine stimulated secretion of a NaCl-rich hyposmotic saliva containing (mM): Na(+) 95 +/- 2; K(+) 38 +/- 1; Cl(-) 145 +/- 3. Saliva collected during serotonin stimulation had a similar composition. Bumetanide decreased secretion rates induced by dopamine and serotonin; secreted saliva had lower Na(+), K(+) and Cl(-) concentrations and osmolarity. Ouabain caused increased secretion rates on a serotonin background. Saliva secreted during dopamine but not serotonin stimulation in the presence of ouabain had lower K(+) and higher Na(+) and Cl(-) concentrations, and was isosmotic. We concluded: The Na(+)-K(+)-2Cl(-) cotransporter is of cardinal importance for electrolyte and fluid secretion. The Na(+)/K(+)-ATPase contributes to apical Na(+) outward transport and Na(+) and K(+) cycling across the basolateral membrane in acinar P-cells. The salivary ducts modify the primary saliva by Na(+) reabsorp...Continue Reading

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Citations

Mar 30, 2007·Acta Veterinaria Scandinavica·Torbjörn S LundströmOve S Wattle
Mar 21, 2009·PLoS Computational Biology·Yuqiao GuJean-Pierre Rospars
Jan 9, 2014·International Journal of Molecular Sciences·Britta TroppmannWolfgang Blenau
Apr 1, 2008·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·David K Lloyd
Jun 20, 2006·Archives of Insect Biochemistry and Physiology·Bernd WalzWolfgang Blenau
Mar 4, 2009·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Carsten HilleCarsten Dosche
Dec 8, 2005·Canadian Journal of Physiology and Pharmacology·Yun DaiJohn H Zhang
Dec 18, 2008·The Journal of Experimental Biology·Cathleen RotteBernd Walz
Feb 2, 2006·The Journal of Experimental Biology·Hidehiro Watanabe, Makoto Mizunami

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