Salivary and lacrimal gland involvement in a patient who had undergone a thyroidectomy and was treated with radioiodine for thyroid cancer

Oral Surgery, Oral Medicine, and Oral Pathology
A MarkitziuR Chisin

Abstract

A patient with bilateral, insidiously developing enlargement of the parotid glands that started 1 year after a total thyroidectomy and ablative radioiodine therapy (200 mCi I131) for papillary carcinoma is presented. The patient displayed prolonged periods of hypothyroidism accompanied by hypercholesterolinemia, notwithstanding hormone replacement therapy. Three years after surgery, parotid and lacrimal gland functions were reduced and fatty degeneration of the parotid parenchyma was demonstrated histologically. The submandibular and sublingual glands were preserved. It is suggested that the hormonal and metabolic derangements are responsible for the glandular dysfunction, rather than a direct effect of iodine on the glands.

References

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Feb 1, 1987·Journal of Dental Research·M M Schubert, K T Izutsu
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Citations

Aug 28, 2013·Annals of Nuclear Medicine·Ugur AcarGökhan Koca
Sep 29, 2001·Thyroid : Official Journal of the American Thyroid Association·A E HeufelderW Joba
Dec 29, 2000·Nuclear Medicine Communications·G ZettinigR Dudczak
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Mar 5, 2013·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Dhanya MuralidharanB V Ajith Kumar
Feb 13, 2016·Ophthalmic Plastic and Reconstructive Surgery·Mohammad Javed Ali
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Jan 21, 2012·Ophthalmic Plastic and Reconstructive Surgery·Matheson A HarrisJennifer A Sivak-Callcott

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