Salivary antioxidants and oxidative stress markers in male smokers

Combinatorial Chemistry & High Throughput Screening
Fatemeh Ahmadi-MotamayelJalal Poorolajal

Abstract

Cigarette smoke free radicals can cause cellular damage and different diseases. All the body fluids have antioxidants which protect against free radicals. The aim of this study was to evaluate salivary total antioxidant capacity and peroxidase, uric acid and malondialdehyde levels in smokers and a nonsmoking control group. Unstimulated saliva was collected from 510 males. A total of 259 subjects were current smokers and 251 were non-smokers. The levels of salivary total antioxidant capacity, uric acid, peroxidase and malondialdehyde were measured using standard procedures. Data were analyzed with t test and ANOVA. The smokers were younger and dental hygiene index was higher than healthy nonsmoking controls. The mean total antioxidant capacity in smokers and nonsmokers was 0.13±0.07 and 0.21±011, respectively (P=0.001). Smokers had significantly lower peroxidase and uric acid levels than healthy controls. In addition, the mean malondialdehyde levels in the smokers and nonsmokers were 4.55 ±2.61 and 2.79 ±2.21, respectively (P=0.001). Cigarette smoke produces free radical and oxidative stress, causing many side effects. Salivary antioxidant levels decreased and malondialdehyde levels increased in smokers, indicating the high oxid...Continue Reading

References

Jul 13, 1999·Archives of Oral Biology·B ZappacostaB Giardina
Jan 25, 2003·Free Radical Biology & Medicine·Abraham Z ReznickRafael M Nagler
Dec 4, 2003·Free Radical Biology & Medicine·Ifat KleinAbraham Z Reznick
Dec 22, 2004·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Yelda KarincaogluMetin Genc
Apr 12, 2005·International Journal of Cardiology·Mustafa KosecikSahabettin Selek
Jan 26, 2006·Gerodontology·Takashi KanehiraManabu Morita
Feb 24, 2006·Journal of Clinical Periodontology·Nurcan BuduneliDavid A Scott
Sep 7, 2006·Journal of Periodontal Research·N GargV Tewari
Oct 19, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Christine A Northrop-Clewes, David I Thurnham
Apr 7, 2007·American Journal of Therapeutics·Jennifier ChávezManuel Valasco
Aug 19, 2007·Archives of Oral Biology·Raymond G SchipperMonique H Vingerhoeds
Nov 7, 2012·Journal of Investigative and Clinical Dentistry·Sudhakara ReddyKoppolu Pradeep
Sep 7, 2013·Chonnam Medical Journal·Fatemeh Ahmadi-MotamayelJalal Poorolajal
Nov 2, 2016·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Fatemeh Ahmadi-MotamayelJalal Poorolajal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Fatemeh Ahmadi-MotamayelJalal Poorolajal
Journal of Dental Research, Dental Clinics, Dental Prospects
Sedigheh BakhtiariZahra Namazi
© 2021 Meta ULC. All rights reserved