Salivary diagnostics of the novel corona virus SARS-CoV-2 (COVID-19)

Oral Diseases
Evangelia MichailidouGeorgios Tzimagiorgis

Abstract

Laboratory testing for SARS-CoV-2 virus and the consequent respiratory coronavirus disease 2019 (COVID-19) is categorized in methods that detect the viral presence and methods that detect antibodies produced in the host as a response to infection. Methods that detect viral presence into the host excretions measure current infection by SARS-CoV-2 whereas the detection of human antibodies exploited against SARS-CoV-2 evaluates the past exposure to the virus. This review provides a comprehensive overview for the use of saliva as a specimen for the detection of SARS-CoV-2, the methods for the salivary diagnostics utilized till very recently and the arisen considerations for the diagnosis of COVID-19 disease. The major advantage of using saliva as a specimen for the detection of SARS-CoV-2 is that saliva collection is a noninvasive method which produces no discomfort to the patient and permits to the patients home self-sampling techniques in order to protect health providers from the exposure to the pathogen. There is an urgent need to increase the active research for the detection of SARS-CoV-2 in the saliva because the non-invasive salivary diagnostics may provide a reliable and cost-effective method suitable for the fast and earl...Continue Reading

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Citations

May 11, 2021·Frontiers in Medicine·Devi Sewvandini Atukorallaya, Ravindra K Ratnayake

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Methods Mentioned

BETA
reverse transcription PCR
PCR
nucleic acid amplification
nucleic

Software Mentioned

CONVAT

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