Abstract
Orocutaneous and pharyngocutaneous fistula (OPCF) is a debilitating complication of head and neck surgery for squamous cell carcinoma (SCC), resulting in delayed adjuvant treatment and prolonged hospitalization. As yet, there is no established test that can help in prompt and accurate diagnosis of OPCF. This study aims to determine the accuracy of bedside blue dye testing and its role as part of an algorithm for early diagnosis. We also analyze the risk factors predisposing to OPCF. Retrospective cohort study from 2012 to 2014. Patients with head and neck SCC who underwent major resection and reconstruction, at risk of OPCF, were included. Results of blue-dye and video-fluoroscopic swallow-studies (VFSS) testing for OPCF were recorded. For the patients that were noted to develop OPCF, the length of time to diagnosis of fistula and subsequent mode of management were examined. Of the 93 patients in this study, 25 (26.9%) developed OPCF. Advanced T-classification (T3/T4) was the only significant predisposing risk factor (p = 0.013). The sensitivity and specificity of the bedside blue dye testing was found to be 36.4% and 100%, respectively. The test positive patients were diagnosed with OPCF at a median of postoperative day (POD) ...Continue Reading
References
Feb 15, 1988·Cancer·L V JohansenO Elbrønd
Feb 1, 1984·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·A M GiordanoG L Adams
Oct 1, 1993·The Laryngoscope·B L MosesB Jones
Mar 26, 1999·Head & Neck·L O Redaelli de ZinisP Nicolai
Oct 3, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·M FriedmanD D Caldarelli
Feb 24, 2001·Head & Neck·J A VirtaniemiV M Kosma
Sep 13, 2002·Critical Care : the Official Journal of the Critical Care Forum·Elise Whitley, Jonathan Ball
Sep 20, 2002·American Journal of Otolaryngology·Levent SaydamAhmet Kizilay
Jan 15, 2003·Archives of Otolaryngology--head & Neck Surgery·Randal S WeberJohn Ensley
Sep 30, 2003·Current Opinion in Otolaryngology & Head and Neck Surgery·Antti A MäkitiePatrick J Gullane
Oct 24, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·L Barlas AydoğanLevent Soylu
Apr 9, 2005·Cancer·Ian GanlyJatin Shah
Nov 9, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jacopo GalliGaetano Paludetti
Apr 3, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Randall P MortonNicholas P McIvor
Nov 14, 2007·Journal of Cancer Research and Therapeutics·S S QureshiA K D'cruz
Feb 22, 2012·The Laryngoscope·Shivam KapilaSian Fairbank
Jun 1, 2012·The Laryngoscope·Hilliary N WhiteEben L Rosenthal
Jun 5, 2013·Head & Neck·Brian TianN Gopalakrishna Iyer
May 3, 2015·Auris, Nasus, Larynx·Ji-Wang LiangYan-Guo Li
Citations
Jan 25, 2019·Head & Neck·Dongbin AhnJin Ho Sohn
Sep 10, 2019·Head & Neck·Farhana GirkarAnil D'Cruz
Aug 31, 2020·Head & Neck·Florent CarsuzaaXavier Dufour
Jun 30, 2019·Head and Neck Pathology·Isabelle KoobUlrich Straßen
Jan 4, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Bina TariqLaura W J Baijens