Salivary gland myoepithelioma variants. Histological, ultrastructural, and immunocytological features.

Virchows Archiv. A, Pathological Anatomy and Histopathology
I DardickB F Burns

Abstract

The histological and ultrastructural features of five major salivary gland tumours, which have little or no evidence of duct- or gland-type differentiation in routine sections, are described. Four of the cases have the tumour cells organized as narrow, anastomosing cords of cells separated by a myxoid and vascularized stroma; we have designated such lesions as reticular-type myoepitheliomas. The fifth case has a solid growth pattern and is largely composed of hyaline cells, that is, a plasmacytoid myoepithelioma. Ultrastructurally, one reticular myoepithelioma reveals myoepithelial cell differentiation with microfilament aggregates, while the other three examples are composed of modified myoepithelial cells displaying widened intercellular spaces, prominent synthesis of extracellular glycosaminoglycans, distinct basal lamina development, and obvious accumulations of cytoplasmic intermediate filaments. In electron micrographs, the modified myoepithelial cells of the plasmacytoid variant closely resemble the tumour cells in the reticular form. Three cases had expression of both glial fibrillary acid protein (GFAP) and vimentin, but only one of the myoepitheliomas contained muscle-specific actin. At least focally, each of the case...Continue Reading

References

Mar 1, 1978·Histopathology·J D Lomax-Smith, J G Azzopardi
Nov 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·S H DairkeeA J Hackett
Feb 1, 1986·International Journal of Pediatric Otorhinolaryngology·J E Lins, D R Gnepp
Jul 1, 1986·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·R B NagleE D Jarasch
Jun 1, 1986·Oral Surgery, Oral Medicine, and Oral Pathology·M MoriM A Meenagham
Aug 1, 1986·Oral Surgery, Oral Medicine, and Oral Pathology·P D Toto, D J Hsu
Oct 1, 1986·International Journal of Oral and Maxillofacial Surgery·H NikaiN Ijuhin
Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·S GeigerG Marshak
Jan 1, 1988·Virchows Archiv. A, Pathological Anatomy and Histopathology·I DardickD L Brown
Jan 1, 1988·Virchows Archiv. A, Pathological Anatomy and Histopathology·B F BurnsW R Parks
Jan 1, 1988·Ultrastructural Pathology·B MackayH Goepfert
Jan 1, 1988·Virchows Archiv. A, Pathological Anatomy and Histopathology·P LeonciniG Gabbiani
May 1, 1985·Head & Neck Surgery·I Dardick, A W van Nostrand
Jun 1, 1985·Histopathology·J M OrensteinA W van Nostrand
Oct 1, 1988·Oral Surgery, Oral Medicine, and Oral Pathology·I Dardick, A W van Nostrand
May 1, 1985·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D MitchellB A Gusterson
Dec 1, 1967·Journal of Ultrastructure Research·G F Smith, P T O'Hara
Feb 1, 1981·Journal of Oral Pathology·J M NeslandM Sobrinho-Simöes
Feb 1, 1982·Cancer·J J Sciubba, R B Brannon

❮ Previous
Next ❯

Citations

Mar 23, 1999·Diagnostic Cytopathology·K WatanabeT Suzuki
Jan 1, 1993·Virchows Archiv. A, Pathological Anatomy and Histopathology·S Di Palma, M Guzzo
Apr 1, 1994·Oral Surgery, Oral Medicine, and Oral Pathology·V C de AraujoN S de Araujo
Jul 1, 1992·European Journal of Cancer. Part B, Oral Oncology·G Seifert
Nov 30, 2002·Oral Oncology·Jan G A M de VisscherIsaäc van der Waal
Sep 1, 1996·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·J E van der Wal, I van der Waal
May 25, 2001·AJR. American Journal of Roentgenology·S TakashimaT Ishiyama
Nov 18, 2009·Cases Journal·Angelos ChatziavramidisThomas Sidiras
Sep 12, 2000·Applied Immunohistochemistry & Molecular Morphology : AIMM·V C de AraújoN S de Araújo
Jul 1, 1992·Ultrastructural Pathology·I DardickT J Colgan
Sep 1, 1995·Ultrastructural Pathology·I Dardick
Jun 5, 2012·Auris, Nasus, Larynx·Irving J Mejía-HernándezKuauhyama Luna-Ortíz
Apr 15, 1999·The British Journal of Oral & Maxillofacial Surgery·A DeanA García-Lopez
Oct 29, 2015·Acta Radiologica·Jianhui DingTongzhen Chen
Jan 22, 2005·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Sherif Said, John Campana
Nov 28, 2006·Annals of Diagnostic Pathology·Stephen B WilliamsGary R Warnock
Aug 9, 2001·International Journal of Surgical Pathology·Maria P. FoschiniVincenzo Eusebi
Oct 1, 2003·Pathology International·Ikuko OgawaTakashi Takata
Jan 1, 2009·Rare Tumors·Hiroshi ShimosawaHiroshi Sakihara
Apr 20, 2004·Advances in Anatomic Pathology·Adnan T Savera, Richard J Zarbo
Jul 5, 2006·The American Journal of Surgical Pathology·Giuseppe PelosiGiuseppe Viale
Jan 1, 1994·Microscopy Research and Technique·R S Redman
Jan 1, 1994·Microscopy Research and Technique·I Dardick, A P Burford-Mason
Jun 8, 2000·The American Journal of Surgical Pathology·A T SaveraD S Klimstra
Feb 27, 2001·The American Journal of Surgical Pathology·H KutznerL Requena
Jun 28, 2015·Head and Neck Pathology·Gwyneth Soon, Fredrik Petersson
Sep 10, 2003·The American Journal of Surgical Pathology·Jason L Hornick, Christopher D M Fletcher
Jan 1, 1993·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·I Dardick, A P Burford-Mason
Feb 20, 2021·The American Journal of Dermatopathology·Tien Anh N TranKonstantinos Linos
Jan 18, 2003·Pathology, Research and Practice·Jorge S Reis-FilhoJosé Manuel Lopes

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
V C de Araújo, N S de Araújo
Virchows Archiv. A, Pathological Anatomy and Histopathology
B F BurnsW R Parks
© 2022 Meta ULC. All rights reserved