Salivary gland transcriptome analysis during Plasmodium infection in malaria vector Anopheles stephensi

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Rajnikant DixitYogesh S Shouche

Abstract

Understanding the tissue-specific molecular cross-talk mechanism during the mosquito-parasite interaction is of prime importance in the design of new strategies for malaria control. Because mosquito salivary glands are the final destination for the parasite maturation and transmission of vector-borne diseases, identification and characterization of salivary genes and their products are equally important in order to access their effect on the infectivity of the parasite. During the last five years there have been several studies on the sialomes of Anopheles mosquitoes, however very limited information is available on the changes in the salivary gland transcriptome in the presence of Plasmodium, and this information is limited to the mosquito Anopheles gambiae. In this study we aimed to explore and identify parasite-induced transcripts from the salivary glands of Anopheles stephensi, using a subtractive hybridization protocol. Ninety-four percent of expressed sequence tags (ESTs) showed close homology to previously known families of mosquito salivary gland secretary proteins, representing the induced expression of alternative splicing and/or additional new members of the protein family. The remaining 6% of ESTs did not yield sign...Continue Reading

References

Dec 1, 1992·Biophysical Journal·S R DurellH R Guy
Jun 1, 1990·Journal of Bioenergetics and Biomembranes·S Hayashi, H C Wu
Feb 17, 1999·Proceedings of the National Academy of Sciences of the United States of America·B ArcáM Coluzzi
Dec 22, 1999·Biochemistry·I M FrancischettiJ M Ribeiro
Apr 27, 2000·Parasitology Today·A GhoshM Jacobs-Lorena
Jun 7, 2000·Proceedings of the National Academy of Sciences of the United States of America·Y BelkaidJ M Ribeiro
Sep 27, 2000·Proceedings of the National Academy of Sciences of the United States of America·F OduolK D Vernick
Nov 9, 2000·Journal of Peptide Science : an Official Publication of the European Peptide Society·L Otvos
Mar 7, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A S Fauci
Apr 18, 2001·International Archives of Allergy and Immunology·F E Simons, Z Peng
Apr 25, 2001·The Plant Journal : for Cell and Molecular Biology·A SernaR D Thompson
Nov 1, 2001·Proceedings of the National Academy of Sciences of the United States of America·A K GhoshM Jacobs-Lorena
May 25, 2002·Nature·Junitsu ItoMarcelo Jacobs-Lorena
Jun 14, 2002·FEBS Letters·Alessandra LanfrancottiBruno Arcà
Aug 22, 2002·EMBO Reports·Stéphanie BlandinElena A Levashina
Sep 6, 2002·Insect Biochemistry and Molecular Biology·J G ValenzuelaJ M C Ribeiro
Nov 8, 2002·Insect Molecular Biology·X-L Zheng, And L Zheng
Jun 27, 2003·Insect Biochemistry and Molecular Biology·Jesus G ValenzuelaJosé M C Ribeiro
Sep 25, 2003·The Journal of Experimental Biology·Anthony A James
Nov 25, 2003·The Journal of Biological Chemistry·Prakash SrinivasanMarcelo Jacobs-Lorena
Nov 25, 2003·The Journal of Biological Chemistry·Eappen G AbrahamMarcelo Jacobs-Lorena
Jan 20, 2004·Insect Molecular Biology·E CalvoO Marinotti
Apr 15, 2004·Genetics·Luciano A MoreiraMarcelo Jacobs-Lorena
May 19, 2004·Insect Biochemistry and Molecular Biology·José M C RibeiroJesus G Valenzuela
May 24, 2005·Molecular and Biochemical Parasitology·Xiaojin XuGeorge Dimopoulos
Oct 11, 2005·The Journal of Experimental Biology·Bruno ArcàJosé M C Ribeiro
Nov 23, 2005·The Journal of Biological Chemistry·Eric CalvoJosé M C Ribeiro
Oct 24, 2006·Cellular Microbiology·Isabelle Rosinski-ChupinPaul T Brey
Dec 13, 2006·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Frédéric SimardTovi Lehmann
Jan 25, 2007·Insect Biochemistry and Molecular Biology·Eric CalvoJosé M C Ribeiro

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Citations

May 11, 2013·Journal of Biosciences·Kaustubh GokhaleYogesh S Shouche
Dec 12, 2012·Proceedings of the National Academy of Sciences of the United States of America·Ana C FigueiredoPedro José Barbosa Pereira
Jan 8, 2013·Vector Borne and Zoonotic Diseases·Aleksandar ZocevicValérie Choumet
Jan 30, 2014·Parasites & Vectors·Rodney Hull, Zodwa Dlamini
Jul 27, 2011·Journal of Insect Physiology·Rajnikant DixitArun Sharma
Feb 21, 2014·The Journal of Investigative Dermatology·Quentin BernardNathalie Boulanger
Feb 26, 2011·Immunological Reviews·Stefanie Steinert, Elena A Levashina

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