Salivary Levels of Hemoglobin for Screening Periodontal Disease: A Systematic Review

International Journal of Dentistry
Yoshiaki NomuraHiroko Miura

Abstract

Periodontal disease is a common inflammatory disease. It affects about 20-50% of global population in both developed and developing countries. Early detection of slight changes of periodontal tissue plays an important role in prevention of onset and progression of periodontal disease. Hence, there is a need of a screening test to assess periodontal tissue for health check-ups. Salivary levels hemoglobin (Hb) has been proposed to assess the conditions of the inflammation of gingiva. The aim of this systematic review was to evaluate and summarize critically the current evidences for Hb as periodontal screening test. We performed a literature search of report published using PubMed databases. A total of 55 articles were retrieved and 16 were selected. Our review focuses on corelation coefficient with periodontal clinical parameters or sensitivity and specificity. As a result, fourteen studies calculated sensitivity and specificity of Hb. Six studies measured salivary levels hemoglobin at laboratory: three studies used polyclonal antibody reactions and other studies used colorimetric tests. Eight studies used paper strip method: 4 studies used monoclonal antibody reaction and 4 studies used colorimetric tests. Youden's indexes by a...Continue Reading

References

Nov 1, 1978·Community Dentistry and Oral Epidemiology·B A BurtS A Eklund
Nov 1, 1978·Journal of Periodontology·B H Abbott, R G Caffesse
Jan 16, 2007·Journal of Oral Science·Yoshiaki NomuraKyuichi Kamoi
Nov 4, 2010·Journal of Periodontology·Yoshihiro ShimazakiYoshihisa Yamashita
Oct 28, 2011·Archives of Oral Biology·Yoshiaki NomuraHiromasa Yoshie
Apr 4, 2017·Journal of Oral Science·Ayako OkadaNobuhiro Hanada

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