Salmon allergen exposure, occupational asthma, and respiratory symptoms among salmon processing workers

American Journal of Industrial Medicine
Anna Dahlman-HöglundEva Andersson

Abstract

This investigation was triggered by three cases of asthma-about 10% of the workforce-occurring in a salmon processing plant over a short period of time. The aim of the investigation was to characterize the work exposure of inhalable organic particles with personal measurements. Respiratory symptoms at work among workers were also assessed. Exposures to airborne salmon allergen, airborne mold spores, and endotoxin in water and air were measured during work. To assess the Atlantic salmon (Salmo salar) Sal s 1 allergen exposure a polyclonal sandwich enzyme-linked immunosorbent assay (ELISA) was developed. Current workers (n = 26) answered questionnaires and underwent allergy and lung function tests. Using the sensitive ELISA method (0.05 ng/ml), we found that workers were exposed to high levels of salmon major allergen at the filleting machine and at the filleting table. Airborne endotoxin levels were low, and mold levels were elevated. Only the three initial asthma cases had IgE to salmon. Of the other workers, 65% reported respiratory symptoms at work. These had lower pulmonary function than workers without such symptoms. We developed a sensitive method to measure salmon antigen in air and found that filleting workers were most ...Continue Reading

References

Sep 3, 1987·The New England Journal of Medicine·R M CastellanJ L Hankinson
Sep 1, 1984·The Journal of Allergy and Clinical Immunology·A CartierJ Y Dubois
Sep 16, 1995·Lancet·J D DouglasD Franklin
Jul 1, 1996·Critical Reviews in Food Science and Nutrition·S B LehrerG Reese
Oct 1, 1996·Scandinavian Journal of Immunology·C D LindstrømS Elsayed
Aug 1, 1997·Allergy·J RodríguezZ Bensabat
Jan 7, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A RenströmP Malmberg
Feb 15, 2001·American Journal of Industrial Medicine·E Melbostad, W Eduard
Aug 21, 2001·Occupational and Environmental Medicine·M F JeebhayA L Lopata
Sep 13, 2002·Canadian Journal of Microbiology·William B AndersonColin I Mayfield
Aug 13, 2004·American Journal of Industrial Medicine·Kari Kulvik Heldal, Wijnand Eduard
May 14, 2005·Journal of Occupational and Environmental Medicine·Berit BangTine Rasmussen
Dec 13, 2005·The Journal of Allergy and Clinical Immunology·Thien Van DoCurt Endresen
Apr 11, 2008·Toxicology and Applied Pharmacology·Anett K LarsenBerit Bang
Aug 30, 2008·American Journal of Industrial Medicine·Mohamed F JeebhayAndreas L Lopata
Mar 20, 2009·Journal of Toxicology and Environmental Health. Part a·Berit BangLisbeth Aasmoe
Mar 1, 1993·The European Respiratory Journal·P H QuanjerJ C Yernault

❮ Previous
Next ❯

Citations

Apr 12, 2013·Current Allergy and Asthma Reports·Andreas L Lopata, Mohamed F Jeebhay
May 25, 2013·The Annals of Occupational Hygiene·Anna Dahlman-HöglundEva Andersson
Feb 27, 2013·Clinical Reviews in Allergy & Immunology·Michael F Sharp, Andreas L Lopata
Dec 7, 2013·American Journal of Industrial Medicine·Olga ShiryaevaBerit Elisabeth Bang
Nov 17, 2012·Clinics in Chest Medicine·Anthony M Szema
Jan 25, 2017·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J N StephenA L Lopata
Oct 12, 2018·ERJ Open Research·Gro TjalvinJorunn Kirkeleit
Dec 14, 2018·Current Treatment Options in Allergy·Joyce A M Emons, Roy Gerth van Wijk
Jun 4, 2020·Annals of Work Exposures and Health·Howard J MasonMartie van Tongeren
Oct 23, 2020·Journal of Agromedicine·Anna Dahlman-Höglund, Eva Andersson
Jun 11, 2021·Annals of Work Exposures and Health·Cecilie T HeidelbergLisbeth Aasmoe
May 29, 2014·Journal of Agricultural and Food Chemistry·Zheng LiJianping Wu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.