Salmonella mutagenicity assessment of airborne particulate matter collected from urban areas of Rio Grande do Sul State, Brazil, differing in anthropogenic influences and polycyclic aromatic hydrocarbon levels

Mutation Research
Tatiana S PereiraVera M F Vargas

Abstract

Urban areas are both major sources and major targets of air pollution. The atmospheric environment receives diverse chemical substances, including genotoxic agents that may affect human health. The purpose of this study was to evaluate and compare the atmospheric quality in two urban areas in Rio Grande do Sul State (Brazil), under the influence of greater (Site 1) or lesser (Site 2) anthropogenic sources. Polycyclic aromatic hydrocarbons (PAHs) of environmental interest were quantified and the Salmonella/microsome assay was used for the measurement of mutagenicity. Organic compounds extracted from the airborne particulate matter were analyzed by high-performance liquid chromatography (HPLC) to detect PAHs of interest (known or possible carcinogens). The organic extracts were also tested for mutagenic and cytotoxic activity in the Salmonella/microsome assay with strains TA98, TA100, YG1021 and YG1024, with or without S9 activation. At Site 1, benzo[ghi]perylene (BghiP) and indeno[1,2,3-cd]pyrene (IP) were found at higher concentrations and mutagenicity (revertants per μg extract) varied from 1.0±0.25 (TA98, no S9) to 5.2±0.45 (TA98, S9). At Site 2, BghiP and IP were present in larger amounts and the mutagenic responses ranged f...Continue Reading

References

May 1, 1983·Mutation Research·D M Maron, B N Ames
May 10, 2002·Chemosphere·Milena B FernandesJ N Cardoso
Sep 16, 2003·Mutation Research·Adriana Ducatti, Vera Maria Ferrão Vargas
Dec 2, 2004·Mutation Research·Larry D ClaxtonSarah H Warren
Jan 26, 2005·Environmental Science & Technology·Fabienne Reisen, Janet Arey
Sep 16, 2005·The Science of the Total Environment·Martina RehwagenAlicia Ronco
Apr 6, 2007·Mutation Research·Tatiana da Silva PereiraVera Maria Ferrão Vargas
Apr 25, 2007·Mutation Research·Larry D Claxton, George M Woodall
Dec 18, 2007·The Science of the Total Environment·Vera Maria Ferrão VargasNara Regina Terra
Jun 9, 2009·Environment International·Mariana V CoronasVera M F Vargas

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Citations

Jun 4, 2013·Ecotoxicology and Environmental Safety·Kelly Cristina Tagliari de BritoVera Maria Ferrão Vargas
Jan 1, 2012·Journal of Environmental Sciences (China)·Badar GhauriChristian Khalil
Mar 3, 2015·Mutation Research. Genetic Toxicology and Environmental Mutagenesis·Cristiane Silva da SilvaVera Maria Ferrão Vargas
Jul 17, 2012·Chemosphere·Andréia Torres LemosVera Maria Ferrão Vargas
Feb 14, 2012·Environmental Pollution·Márcia Isabel KäfferVera Maria Ferrão Vargas
Feb 12, 2013·Ecotoxicology and Environmental Safety·Tatiana S PereiraVera M F Vargas
Apr 16, 2013·FEMS Microbiology Letters·Hani A Alhadrami, Graeme I Paton
Jun 28, 2016·Chemosphere·Andréia Torres LemosVera Maria Ferrão Vargas

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