Same Redox Evidence But Different Physiological "Stories": The Rashomon Effect in Biology

BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology
Michalis G Nikolaidis, Nikos V Margaritelis

Abstract

The Rashomon effect - a phenomenon studied in the arts and social sciences - occurs when the same event is given contradictory interpretations by different individuals involved. The effect was named after Akira Kurosawa's 1950 film Rashomon, in which a murder is described in four contradictory ways by four witnesses. In the film, a samurai has been killed under mysterious circumstances. Four people give contradictory reports about the crime. In particular, the samurai's wife claims that she was sexually abused by a bandit, fainted, and then awoke to find her husband dead; the bandit claims that he seduced the wife and challenged the samurai in a battle to victory or at least to an honorable death; the woodcutter (who may have been an onlooker) claims that he witnessed the rape and murder but was not involved; and the dead samurai's spirit claims that he committed suicide. The Rashomon effect is not only about constructing different versions of the world based on differences in perspective; it occurs when such differences appear together with the absence of evidence to assess any version of the truth, plus "the social pressure for closure on the question." In this commentary, we describe the relevance of the Rashomon effect beyo...Continue Reading

References

Apr 28, 2012·The Journal of Experimental Biology·Michalis G NikolaidisIoannis S Vrabas
Feb 7, 2014·PLoS Computational Biology·Weixiong Zhang
Jan 2, 2016·Cellular Signalling·Nikos V MargaritelisMichalis G Nikolaidis
Feb 9, 2016·Free Radical Biology & Medicine·N V MargaritelisM G Nikolaidis
Apr 22, 2017·Trends in Molecular Medicine·Iok In Christine Chio, David A Tuveson
May 12, 2017·Cold Spring Harbor Perspectives in Medicine·Michael J Joyner, Jerome A Dempsey

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Citations

May 27, 2020·International Journal of Sports Medicine·Michalis G NikolaidisAntonios Matsakas
Nov 9, 2018·Antioxidants·Christine RamponSophie Vriz
Jul 20, 2020·Free Radical Biology & Medicine·Nikos V MargaritelisMichalis G Nikolaidis
Sep 4, 2021·IUBMB Life·Nikos V MargaritelisMichalis G Nikolaidis

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