Same Site Recurrence is More Frequent After Endovenous Laser Ablation Compared with High Ligation and Stripping of the Great Saphenous Vein: 5 year Results of a Randomized Clinical Trial (RELACS Study)

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
Knuth RassThomas Vogt

Abstract

To compare the long-term clinical efficacy of endovenous laser ablation (EVLA) with high ligation and stripping (HLS) as standard treatment for great saphenous vein (GSV) incompetence. Investigator initiated two centre randomized controlled trial with 5 year follow up. Interventions were performed on ambulatory and hospitalized patients at two vein centres, a university dermatology department (EVLA) and a specialized vein clinic (HLS). Four hundred patients suffering from GSV incompetence were assigned to EVLA or HLS of the GSV. One hundred and eighty five and 161 patients (=limbs), respectively, were treated per protocol. Main outcome measures were clinically recurrent varicose veins after surgery (REVAS classification, primary study objective), Duplex detected saphenofemoral recurrence, clinical venous severity scoring (Homburg Varicose Vein Severity Score), quality of life (Chronic Venous Insufficiency Questionnaire 2), side effects, and patient satisfaction 5 years after treatment. Two hundred and eighty one legs (81% of the study population) were evaluated with a median follow up of 60.4 (EVLA) and 60.7 months (HLS). Overall, REVAS was similarly observed in both groups: 45% (EVLA) and 54% (HLS), p = .152. Patients of the E...Continue Reading

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Citations

Feb 27, 2016·Phlebology·James A Lawson, Irwin M Toonder
Feb 27, 2016·Phlebology·Mark H Meissner
May 12, 2016·The British Journal of Surgery·O Nelzén
Apr 12, 2019·The British Journal of Surgery·S WelshE McLennan
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Aug 24, 2021·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Matthew S SussmanJose I Almeida

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