San Antonio heart study diabetes prediction model applicable to a Middle Eastern population? Tehran glucose and lipid study

International Journal of Public Health
Mohammadreza BozorgmaneshFereidoun Azizi

Abstract

To assess the validity of the San Antonio heart study (SAHS) diabetes prediction model in a large representative Iranian population. A risk function derived from data in the SAHS to predict the 7.5-year risk of diabetes, was tested for its ability to predict incident diabetes in 3,242 individuals aged >or=20 years. The performance or ability to accurately predict diabetes risk, of the SAHS function compared with the performance of risk functions developed specifically from the Tehran lipid and glucose study. Comparisons included goodness of fit, discrimination, and calibration. The participants were followed for 6.3 years. The area under the receiver operating characteristic curve (AROC) for diabetes of SAHS model was 0.83 (95% CI 0.80-0.86). The model overestimated the risk of diabetes in TLGS population with the overall bias of 111%. After the recalibration, the model-predicted probability agreed well with the actual observed 6-year risk of diabetes. The American SAHS was a prediction model for diabetes with good discrimination in an Iranian target population after calibration.

References

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Citations

Nov 30, 2011·BMJ : British Medical Journal·Douglas NobleTrisha Greenhalgh
May 28, 2011·Acta Diabetologica·Mohammadreza BozorgmaneshFereidoun Azizi
Jun 2, 2011·Diabetic Medicine : a Journal of the British Diabetic Association·Mohammadreza BozorgmaneshFereidoun Azizi
Jan 7, 2017·International Journal of Endocrinology and Metabolism·Mahnaz BarkhordariMohammadreza Bozorgmanesh

Related Concepts

Blood Glucose
Body Measure Procedure
Diabetes Mellitus, Non-Insulin-Dependent
Lipids
Receiver Operating Characteristic
Two-Parameter Models
Age Distribution
Sex Distribution
Diabetes
Cardiac Function

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