Sarcoidosis manifesting as massive splenomegaly: a rare occurrence

The American Journal of the Medical Sciences
Anant MohanAmit Kumar Dutta

Abstract

Sarcoidosis is a multisystemic granulomatous disease of unknown origin occurring worldwide and affecting people of all races and ages. This disease manifests most frequently with bilateral hilar lymphadenopathy, pulmonary infiltrates, and skin and ocular lesions. Granulomatous inflammation of the spleen is common in patients with sarcoidosis, but splenic enlargement is unusual and massive splenomegaly quite rare. Splenomegaly is usually homogeneous, but multiple low-attenuating nodular lesions are occasionally seen and easily mistaken for lymphoma, metastases, or infections such as tuberculosis. We describe an unusual case of sarcoidosis in a woman who presented with massive splenomegaly with extensive nodularity that cleared completely with corticosteroid therapy.

References

Jul 1, 1992·Southern Medical Journal·J FordiceP J Asimacopoulos
Jan 1, 1991·Radiology·A R BrittJ H Ellis
Jul 1, 1988·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·F J AlvarezM Biosca
Jul 1, 1986·Journal of Computer Assisted Tomography·D MathieuN Vasile
Jan 1, 1980·Archives of Internal Medicine·Y P Kataria, M E Whitcomb
Mar 8, 2000·American Journal of Hematology·M Z HaranA Berrebi

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Citations

Jan 25, 2008·Der Pathologe·T RüdigerA Marx
Mar 4, 2009·World Journal of Surgical Oncology·Sandeep P JoglekarJerome H Pereira
Jan 5, 2012·Internal Medicine·Sayaka KawanoKazuo Kitamura
Sep 7, 2012·Case Reports in Rheumatology·Ishita PatelAlan Steuer
Jul 27, 2010·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Kristin Loening MacArthurGeorge Yung-Hsing Wu
Oct 5, 2010·La Revue de médecine interne·C Chapelon Abric
Jul 19, 2012·International Journal of Dermatology·Nicolas KlugerBernard Guillot
Jul 10, 2010·Pediatric Hematology and Oncology·Abdulrahman AlsultanSarah Alsubaie

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