Sarcoidosis with orbital tumor outside the lacrimal gland: initial manifestation in 2 elderly white women

Archives of Ophthalmology
E A PetersonN Mamalis

Abstract

Two elderly white women (aged 72 and 87 years) were first seen with painless, unilateral orbital swelling. Orbital scanning revealed masses infiltrating the soft tissue around the eye. Biopsy results showed nodular, noncaseating granulomas consistent with sarcoidosis. One patient's workup revealed systemic manifestations of sarcoidosis at the time of examination with hilar lymphadenopathy noted on gallium scan; the other refused a complete systemic workup. The orbital tumors resolved with systemic prednisone therapy. To our knowledge, our 87-year-old patient is the oldest to be seen with orbital sarcoidosis. These 2 patients demonstrate that this diagnosis must be considered with orbital tumors in the elderly and in unusual locations, such as these which occurred outside the lacrimal gland.

Citations

Dec 1, 2007·International Ophthalmology Clinics·Ronald A Braswell, Lanning B Kline
Jun 15, 2016·Case Reports in Ophthalmological Medicine·Sílvia Miguéis Picado PetrarolhaPedro Martins Tavares Scianni Morais
Jan 23, 2004·AJR. American Journal of Roentgenology·J Keith SmithMauricio Castillo
Aug 5, 2000·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Z A ShaikhN S Lincoff
May 8, 2010·Neuroradiology·Saifuddin T VohraBarton F Branstetter
Dec 13, 2006·Ocular Immunology and Inflammation·Sonia AttiaMoncef Khairallah
Feb 15, 2013·Journal of the American Geriatrics Society·Satoshi YamaguchiKazuyuki Tobe

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