Sarcomatoid transitional cell carcinoma of the renal pelvis. A report of five cases with clinical, pathological, immunohistochemical and DNA ploidy analysis

Pathology, Research and Practice
Antonio Lopez-BeltranL Vicioso-Recio

Abstract

Sarcomatoid transitional cell carcinoma of the renal pelvis is a rare neoplasm with only 7 well illustrated examples reported. These tumours can assume a partial or complete spindle cell pattern of growth, leading to the erroneous classification as sarcomas. We describe the clinic-pathologic features of five additional examples of sarcomatoid carcinoma of the renal pelvis observed in three males and two females. The age ranged from 65-to-82 years-old (mean 71.6). All these patients were treated by nephrectomy and died of disease between 6 and 20 months (mean 11.2) after the onset of symptoms. An immunohistochemical study demonstrated coexpression of keratins, epithelial membrane antigen and vimentin. The image DNA ploidy of all the tumours showed an aneuploid pattern.

References

Oct 1, 1979·The American Journal of Surgical Pathology·K H LasserJ Higgins
May 1, 1984·Cancer·M W KaufmanJ L Hoehn
Nov 1, 1983·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D W HedleyE A Musgrove
Oct 1, 1983·Urology·K T ChenR J DeKlotz
Sep 15, 1995·Cancer·P A DundoreD G Bostwick

❮ Previous
Next ❯

Citations

Feb 14, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Delia Perez-MontielSaul Suster
Jan 1, 2015·World Journal of Surgical Oncology·Jitao WuZhenli Gao
Nov 29, 2017·Toxins·Diana Herman, Peter Mantle
Feb 20, 2002·International Journal of Urology : Official Journal of the Japanese Urological Association·T HisatakiH Iwaki
Jul 8, 2000·Pathology International·Y SekidoY Tsutsumi
Apr 8, 2006·The Journal of Urology·Anastasia M Canacci, Gregory T MacLennan
Sep 12, 2018·Minerva urologica e nefrologica = The Italian journal of urology and nephrology·Guglielmo ManticaCarlo Terrone
Mar 1, 2005·International Journal of Urology : Official Journal of the Japanese Urological Association·Mustafa Fuat AcikalinCavit Can
Nov 8, 2007·BJU International·Antonio Lopez-BeltranRodolfo Montironi
Jul 28, 2005·International Journal of Urology : Official Journal of the Japanese Urological Association·Nobuyuki ShimasakiTaro Shuin
Jan 4, 2007·International Journal of Urology : Official Journal of the Japanese Urological Association·Naruyasu MasueTakashi Deguchi
Apr 14, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Justin S BrandtNadav Schwartz
Jun 20, 2014·World Journal of Clinical Cases·Sergio Fernández-PelloCarmen Luz Menéndez
Jun 25, 2014·Oncology Letters·Biao DongHong-Lan Zhou
Oct 10, 2007·Archives of Pathology & Laboratory Medicine·Andrew L Folpe, Kumarasen Cooper
Jun 19, 2007·Human Pathology·Sarah LottLiang Cheng

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Urology : Official Journal of the Japanese Urological Association
Mustafa Fuat AcikalinCavit Can
The Journal of Urology
Anastasia M Canacci, Gregory T MacLennan
Contemporary Oncology Współczesna Onkologia
Xiao-Yong ShenJin Wang
Journal of Radiology Case Reports
Michael ReiterArthur Clarkson
© 2021 Meta ULC. All rights reserved